Interleukin-1 receptor antagonist protein (IL-1RN) (IL-1ra) (IRAP) (ICIL-1RA) (IL1 inhibitor) (Anakinra)
1_MEICR 6_ GLRSH 11_ LITLL 16_ LFLFH 21_ SETIC 26_ RPSGR 31_ KSSKM 36_ QAFRI 41_ WDVNQ 46_ KTFYL 51_ RNNQL 56_ VAGYL 61_ QGPNV 66_ NLEEK 71_ IDVVP 76_ IEPHA 81_ LFLGI 86_ HGGKM 91_ CLSCV 96_ KSGDE 101_ TRLQL 106_ EAVNI 111_ TDLSE 116_ NRKQD 121_ KRFAF 126_ IRSDS 131_ GPTTS 136_ FESAA 141_ CPGWF 146_ LCTAM 151_ EADQP 156_ VSLTN 161_ MPDEG 166_ VMVTK 171_FYFQE
1: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens