Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3)
1_MATNI 6_ EQIFR 11_ SFVVS 16_ KFREI 21_ QQELS 26_ SGRNE 31_ GQLNG 36_ ETNTP 41_ IEGNQ 46_ AGDAA 51_ ASARS 56_ LPNEE 61_ IVQKI 66_ EEVLS 71_ GVLDT 76_ ELRYK 81_ PDLKE 86_ GSRKS 91_ RCVSV 96_ QTDPT 101_ DEIPT 106_ KKSKK 111_ HKKHK 116_ NKKKK 121_ KKKEK 126_ EKKYK 131_ RQPEE 136_ SESKT 141_ KSHDD 146_ GNIDL 151_ ESDSF 156_ LKFDS 161_ EPSAV 166_ ALELP 171_ TRAFG 176_ PSETN 181_ ESPAV 186_ VLEPP 191_ VVSME 196_ VSEPH 201_ ILETL 206_ KPATK 211_ TAELS 216_ VVSTS 221_ VISEQ 226_ SEQSV 231_ AVMPE 236_ PSMTK 241_ ILDSF 246_ AAAPV 251_ PTTTL 256_ VLKSS 261_ EPVVT 266_ MSVEY 271_ QMKSV 276_ LKSVE 281_ STSPE 286_ PSKIM 291_ LVEPP 296_ VAKVL 301_ EPSET 306_ LVVSS 311_ ETPTE 316_ VYPEP 321_ STSTT 326_ MDFPE 331_ SSAIE 336_ ALRLP 341_ EQPVD 346_ VPSEI 351_ ADSSM 356_ TRPQE 361_ LPELP 366_ KTTAL 371_ ELQES 376_ SVASA 381_ MELPG 386_ PPATS 391_ MPELQ 396_ GPPVT 401_ PVLEL 406_ PGPSA 411_ TPVPE 416_ LPGPL 421_ STPVP 426_ ELPGP 431_ PATAV 436_ PELPG 441_ PSVTP 446_ VPQLS 451_ QELPG 456_ LPAPS 461_ MGLEP 466_ PQEVP 471_ EPPVM 476_ AQELP 481_ GLPLV 486_ TAAVE 491_ LPEQP 496_ AVTVA 501_ MELTE 506_ QPVTT 511_ TELEQ 516_ PVGMT 521_ TVEHP 526_ GHPEV 531_ TTATG 536_ LLGQP 541_ EATMV 546_ LELPG 551_ QPVAT 556_ TALEL 561_ PGQPS 566_ VTGVP 571_ ELPGL 576_ PSATR 581_ ALELS 586_ GQPVA 591_ TGALE 596_ LPGPL 601_ MAAGA 606_ LEFSG 611_ QSGAA 616_ GALEL 621_ LGQPL 626_ ATGVL 631_ ELPGQ 636_ PGAPE 641_ LPGQP 646_ VATVA 651_ LEISV 656_ QSVVT 661_ TSELS 666_ TMTVS 671_ QSLEV 676_ PSTTA 681_ LESYN 686_ TVAQE 691_ LPTTL 696_ VGETS 701_ VTVGV 706_ DPLMA 711_ PESHI 716_ LASNT 721_ METHI 726_ LASNT 731_ MDSQM 736_ LASNT 741_ MDSQM 746_ LASNT 751_ MDSQM 756_ LASST 761_ MDSQM 766_ LATSS 771_ MDSQM 776_ LATSS 781_ MDSQM 786_ LATST 791_ MDSQM 796_ LATSS 801_ MDSQM 806_ LATSS 811_ MDSQM 816_ LATSS 821_ MDSQM 826_ LATSS 831_ MDSQM 836_ LATST 841_ MDSQM 846_ LATST 851_ MDSQM 856_ LATSS 861_ MDSQM 866_ LASGT 871_ MDSQM 876_ LASGT 881_ MDAQM 886_ LASGT 891_ MDAQM 896_ LASST 901_ QDSAM 906_ LGSKS 911_ PDPYR 916_ LAQDP 921_ YRLAQ 926_ DPYRL 931_ GHDPY 936_ RLGHD 941_ AYRLG 946_ QDPYR 951_ LGHDP 956_ YRLTP 961_ DPYRM 966_ SPRPY 971_ RIAPR 976_ SYRIA 981_ PRPYR 986_ LAPRP 991_ LMLAS 996_ RRSMM 1001_ MSYAA 1006_ ERSMM 1011_ SSYER 1016_ SMMSY 1021_ ERSMM 1026_ SPMAE 1031_ RSMMS 1036_ AYERS 1041_ MMSAY 1046_ ERSMM 1051_ SPMAE 1056_ RSMMS 1061_ AYERS 1066_ MMSAY 1071_ ERSMM 1076_ SPMAD 1081_ RSMMS 1086_ MGADR 1091_ SMMSS 1096_ YSAAD 1101_ RSMMS 1106_ SYSAA 1111_ DRSMM 1116_ SSYTA 1121_ DRSMM 1126_ SMAAD 1131_ SYTDS 1136_ YTDTY 1141_ TEAYM 1146_ VPPLP 1151_ PEEPP 1156_ TMPPL 1161_ PPEEP 1166_ PMTPP 1171_ LPPEE 1176_ PPEGP 1181_ ALPTE 1186_ QSALT 1191_ AENTW 1196_ PTEVP 1201_ SSPSE 1206_ ESVSQ 1211_ PEPPV 1216_ SQSEI 1221_ SEPSA 1226_ VPTDY 1231_ SVSAS 1236_ DPSVL 1241_ VSEAA 1246_ VTVPE 1251_ PPPEP 1256_ ESSIT 1261_ LTPVE 1266_ SAVVA 1271_ EEHEV 1276_ VPERP 1281_ VTCMV 1286_ SETPA 1291_ MSAEP 1296_ TVLAS 1301_ EPPVM 1306_ SETAE 1311_ TFDSM 1316_ RASGH 1321_ VASEV 1326_ STSLL 1331_ VPAVT 1336_ TPVLA 1341_ ESILE 1346_ PPAMA 1351_ APESS 1356_ AMAVL 1361_ ESSAV 1366_ TVLES 1371_ STVTV 1376_ LESST 1381_ VTVLE 1386_ PSVVT 1391_ VPEPP 1396_ VVAEP 1401_ DYVTI 1406_ PVPVV 1411_ SALEP 1416_ SVPVL 1421_ EPAVS 1426_ VLQPS 1431_ MIVSE 1436_ PSVSV 1441_ QESTV 1446_ TVSEP 1451_ AVTVS 1456_ EQTQV 1461_ IPTEV 1466_ AIEST 1471_ PMILE 1476_ SSIMS 1481_ SHVMK 1486_ GINLS 1491_ SGDQN 1496_ LAPEI 1501_ GMQEI 1506_ ALHSG 1511_ EEPHA 1516_ EEHLK 1521_ GDFYE 1526_ SEHGI 1531_ NIDLN 1536_ INNHL 1541_ IAKEM 1546_ EHNTV 1551_ CAAGT 1556_ SPVGE 1561_ IGEEK 1566_ ILPTS 1571_ ETKQR 1576_ TVLDT 1581_ YPGVS 1586_ EADAG 1591_ ETLSS 1596_ TGPFA 1601_ LEPDA 1606_ TGTSK 1611_ GIEFT 1616_ TASTL 1621_ SLVNK 1626_ YDVDL 1631_ SLTTQ 1636_ DTEHD 1641_ MVIST 1646_ SPSGG 1651_ SEADI 1656_ EGPLP 1661_ AKDIH 1666_ LDLPS 1671_ NNNLV 1676_ SKDTE 1681_ EPLPV 1686_ KESDQ 1691_ TLAAL 1696_ LSPKE 1701_ SSGGE 1706_ KEVPP 1711_ PPKET 1716_ LPDSG 1721_ FSANI 1726_ EDINE 1731_ ADLVR 1736_ PLLPK 1741_ DMERL 1746_ TSLRA 1751_ GIEGP 1756_ LLASD 1761_ VGRDR 1766_ SAASP 1771_ VVSSM 1776_ PERAS 1781_ ESSSE 1786_ EKDDY 1791_ EIFVK 1796_ VKDTH 1801_ EKSKK 1806_ NKNRD 1811_ KGEKE 1816_ KKRDS 1821_ SLRSR 1826_ SKRSK 1831_ SSEHK 1836_ SRKRT 1841_ SESRS 1846_ RARKR 1851_ SSKSK 1856_ SHRSQ 1861_ TRSRS 1866_ RSRRR 1871_ RRSSR 1876_ SRSKS 1881_ RGRRS 1886_ VSKEK 1891_ RKRSP 1896_ KHRSK 1901_ SRERK 1906_ RKRSS 1911_ SRDNR 1916_ KTVRA 1921_ RSRTP 1926_ SRRSR 1931_ SHTPS 1936_ RRRRS 1941_ RSVGR 1946_ RRSFS 1951_ ISPSR 1956_ RSRTP 1961_ SRRSR 1966_ TPSRR 1971_ SRTPS 1976_ RRSRT 1981_ PSRRS 1986_ RTPSR 1991_ RSRTP 1996_ SRRRR 2001_ SRSVV 2006_ RRRSF 2011_ SISPV 2016_ RLRRS 2021_ RTPLR 2026_ RRFSR 2031_ SPIRR 2036_ KRSRS 2041_ SERGR 2046_ SPKRL 2051_ TDLDK 2056_ AQLLE 2061_ IAKAN 2066_ AAAMC 2071_ AKAGV 2076_ PLPPN 2081_ LKPAP 2086_ PPTIE 2091_ EKVAK 2096_ KSGGA 2101_ TIEEL 2106_ TEKCK 2111_ QIAQS 2116_ KEDDD 2121_ VIVNK 2126_ PHVSD 2131_ EEEEE 2136_ PPFYH 2141_ HPFKL 2146_ SEPKP 2151_ IFFNL 2156_ NIAAA 2161_ KPTPP 2166_ KSQVT 2171_ LTKEF 2176_ PVSSG 2181_ SQHRK 2186_ KEADS 2191_ VYGEW 2196_ VPVEK 2201_ NGEEN 2206_ KDDDN 2211_ VFSSN 2216_ LPSEP 2221_ VDIST 2226_ AMSER 2231_ ALAQK 2236_ RLSEN 2241_ AFDLE 2246_ AMSML 2251_ NRAQE 2256_ RIDAW 2261_ AQLNS 2266_ IPGQF 2271_ TGSTG 2276_ VQVLT 2281_ QEQLA 2286_ NTGAQ 2291_ AWIKK 2296_ DQFLR 2301_ AAPVT 2306_ GGMGA 2311_ VLMRK 2316_ MGWRE 2321_ GEGLG 2326_ KNKEG 2331_ NKEPI 2336_ LVDFK 2341_ TDRKG 2346_ LVAVG 2351_ ERAQK 2356_ RSGNF 2361_ SAAMK 2366_ DLSGK 2371_ HPVSA 2376_ LMEIC 2381_ NKRRW 2386_ QPPEF 2391_ LLVHD 2396_ SGPDH 2401_ RKHFL 2406_ FRVLR 2411_ NGALT 2416_ RPNCM 2421_FFLNR
1: RNA-binding protein that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. Specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Probably acts by facilitating the interaction between Serine/arginine-rich proteins such as SRSF2 and the RNA polymerase II. Also binds to DNA; binds to the consensus DNA sequence: 5'-GA[GT]AN[CG][AG]CC-3'. May indirectly repress hepatitis B virus (HBV) core promoter activity and transcription of HBV genes and production of HBV virions. Essential for correct RNA splicing of multiple genes critical for brain development, neuronal migration and metabolism, including TUBG1, FLNA, PNKP, WDR62, PSMD3, PCK2, PFKL, IDH2, and ACY1 (PubMed:27545680)