Gene name: CD58

Uniprot entry:

P19256

Protein names:

Lymphocyte function-associated antigen 3 (Ag3) (Surface glycoprotein LFA-3) (CD antigen CD58)

Protein sequence:

1_MVAGS 6_ DAGRA 11_ LGVLS 16_ VVCLL 21_ HCFGF 26_ ISCFS 31_ QQIYG 36_ VVYGN 41_ VTFHV 46_ PSNVP 51_ LKEVL 56_ WKKQK 61_ DKVAE 66_ LENSE 71_ FRAFS 76_ SFKNR 81_ VYLDT 86_ VSGSL 91_ TIYNL 96_ TSSDE 101_ DEYEM 106_ ESPNI 111_ TDTMK 116_ FFLYV 121_ LESLP 126_ SPTLT 131_ CALTN 136_ GSIEV 141_ QCMIP 146_ EHYNS 151_ HRGLI 156_ MYSWD 161_ CPMEQ 166_ CKRNS 171_ TSIYF 176_ KMEND 181_ LPQKI 186_ QCTLS 191_ NPLFN 196_ TTSSI 201_ ILTTC 206_ IPSSG 211_ HSRHR 216_ YALIP 221_ IPLAV 226_ ITTCI 231_ VLYMN 236_ GILKC 241_DRKPD

Protein annotations

Protein functions:

1: Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells