Gene name: SRM

Uniprot entry:

P19623

Protein names:

Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase)

Protein sequence:

1_MEPGP 6_ DGPAA 11_ SGPAA 16_ IREGW 21_ FRETC 26_ SLWPG 31_ QALSL 36_ QVEQL 41_ LHHRR 46_ SRYQD 51_ ILVFR 56_ SKTYG 61_ NVLVL 66_ DGVIQ 71_ CTERD 76_ EFSYQ 81_ EMIAN 86_ LPLCS 91_ HPNPR 96_ KVLII 101_ GGGDG 106_ GVLRE 111_ VVKHP 116_ SVESV 121_ VQCEI 126_ DEDVI 131_ QVSKK 136_ FLPGM 141_ AIGYS 146_ SSKLT 151_ LHVGD 156_ GFEFM 161_ KQNQD 166_ AFDVI 171_ ITDSS 176_ DPMGP 181_ AESLF 186_ KESYY 191_ QLMKT 196_ ALKED 201_ GVLCC 206_ QGECQ 211_ WLHLD 216_ LIKEM 221_ RQFCQ 226_ SLFPV 231_ VAYAY 236_ CTIPT 241_ YPSGQ 246_ IGFML 251_ CSKNP 256_ STNFQ 261_ EPVQP 266_ LTQQQ 271_ VAQMQ 276_ LKYYN 281_ SDVHR 286_ AAFVL 291_ PEFAR 296_KALND

Protein annotations

Protein functions:

1: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine