Elafin (Elastase-specific inhibitor) (ESI) (Peptidase inhibitor 3) (PI-3) (Protease inhibitor WAP3) (Skin-derived antileukoproteinase) (SKALP) (WAP four-disulfide core domain protein 14)
1_MRASS 6_ FLIVV 11_ VFLIA 16_ GTLVL 21_ EAAVT 26_ GVPVK 31_ GQDTV 36_ KGRVP 41_ FNGQD 46_ PVKGQ 51_ VSVKG 56_ QDKVK 61_ AQEPV 66_ KGPVS 71_ TKPGS 76_ CPIIL 81_ IRCAM 86_ LNPPN 91_ RCLKD 96_ TDCPG 101_ IKKCC 106_ EGSCG 111_MACFV
1: Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Has been shown to inhibit the alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor and to produce a weak inhibition on Kv11.1/KCNH2/ERG1 and on the transient receptor potential cation channel subfamily V member 1 (TRPV1) (PubMed:29483648)