Cyclin-A2 (Cyclin-A) (Cyclin A)
1_MLGNS 6_ APGPA 11_ TREAG 16_ SALLA 21_ LQQTA 26_ LQEDQ 31_ ENINP 36_ EKAAP 41_ VQQPR 46_ TRAAL 51_ AVLKS 56_ GNPRG 61_ LAQQQ 66_ RPKTR 71_ RVAPL 76_ KDLPV 81_ NDEHV 86_ TVPPW 91_ KANSK 96_ QPAFT 101_ IHVDE 106_ AEKEA 111_ QKKPA 116_ ESQKI 121_ EREDA 126_ LAFNS 131_ AISLP 136_ GPRKP 141_ LVPLD 146_ YPMDG 151_ SFESP 156_ HTMDM 161_ SIILE 166_ DEKPV 171_ SVNEV 176_ PDYHE 181_ DIHTY 186_ LREME 191_ VKCKP 196_ KVGYM 201_ KKQPD 206_ ITNSM 211_ RAILV 216_ DWLVE 221_ VGEEY 226_ KLQNE 231_ TLHLA 236_ VNYID 241_ RFLSS 246_ MSVLR 251_ GKLQL 256_ VGTAA 261_ MLLAS 266_ KFEEI 271_ YPPEV 276_ AEFVY 281_ ITDDT 286_ YTKKQ 291_ VLRME 296_ HLVLK 301_ VLTFD 306_ LAAPT 311_ VNQFL 316_ TQYFL 321_ HQQPA 326_ NCKVE 331_ SLAMF 336_ LGELS 341_ LIDAD 346_ PYLKY 351_ LPSVI 356_ AGAAF 361_ HLALY 366_ TVTGQ 371_ SWPES 376_ LIRKT 381_ GYTLE 386_ SLKPC 391_ LMDLH 396_ QTYLK 401_ APQHA 406_ QQSIR 411_ EKYKN 416_ SKYHG 421_ VSLLN 426_PPETL
1: Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle