Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)
1_MGDEK 6_ DSWKV 11_ KTLDE 16_ ILQEK 21_ KRRKE 26_ QEEKA 31_ EIKRL 36_ KNSDD 41_ RDSKR 46_ DSLEE 51_ GELRD 56_ HRMEI 61_ TIRNS 66_ PYRRE 71_ DSMED 76_ RGEED 81_ DSLAI 86_ KPPQQ 91_ MSRKE 96_ KAHHR 101_ KDEKR 106_ KEKRR 111_ HRSHS 116_ AEGGK 121_ HARVK 126_ EKERE 131_ HERRK 136_ RHREE 141_ QDKAR 146_ REWER 151_ QKRRE 156_ MAREH 161_ SRRER 166_ DRLEQ 171_ LERKR 176_ ERERK 181_ MREQQ 186_ KEQRE 191_ QKERE 196_ RRAEE 201_ RRKER 206_ EARRE 211_ VSAHH 216_ RTMRE 221_ DYSDK 226_ VKASH 231_ WSRSP 236_ PRPPR 241_ ERFEL 246_ GDGRK 251_ PGEAR 256_ PAPAQ 261_ KPAQL 266_ KEEKM 271_ EERDL 276_ LSDLQ 281_ DISDS 286_ ERKTS 291_ SAESS 296_ SAESG 301_ SGSEE 306_ EEEEE 311_ EEEEE 316_ EGSTS 321_ EESEE 326_ EEEEE 331_ EEEEE 336_ ETGSN 341_ SEEAS 346_ EQSAE 351_ EVSEE 356_ EMSED 361_ EEREN 366_ ENHLL 371_ VVPES 376_ RFDRD 381_ SGESE 386_ EAEEE 391_ VGEGT 396_ PQSSA 401_ LTEGD 406_ YVPDS 411_ PALSP 416_ IELKQ 421_ ELPKY 426_ LPALQ 431_ GCRSV 436_ EEFQC 441_ LNRIE 446_ EGTYG 451_ VVYRA 456_ KDKKT 461_ DEIVA 466_ LKRLK 471_ MEKEK 476_ EGFPI 481_ TSLRE 486_ INTIL 491_ KAQHP 496_ NIVTV 501_ REIVV 506_ GSNMD 511_ KIYIV 516_ MNYVE 521_ HDLKS 526_ LMETM 531_ KQPFL 536_ PGEVK 541_ TLMIQ 546_ LLRGV 551_ KHLHD 556_ NWILH 561_ RDLKT 566_ SNLLL 571_ SHAGI 576_ LKVGD 581_ FGLAR 586_ EYGSP 591_ LKAYT 596_ PVVVT 601_ LWYRA 606_ PELLL 611_ GAKEY 616_ STAVD 621_ MWSVG 626_ CIFGE 631_ LLTQK 636_ PLFPG 641_ KSEID 646_ QINKV 651_ FKDLG 656_ TPSEK 661_ IWPGY 666_ SELPA 671_ VKKMT 676_ FSEHP 681_ YNNLR 686_ KRFGA 691_ LLSDQ 696_ GFDLM 701_ NKFLT 706_ YFPGR 711_ RISAE 716_ DGLKH 721_ EYFRE 726_ TPLPI 731_ DPSMF 736_ PTWPA 741_ KSEQQ 746_ RVKRG 751_ TSPRP 756_ PEGGL 761_ GYSQL 766_ GDDDL 771_ KETGF 776_ HLTTT 781_ NQGAS 786_AAGPG
1: Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression