Uridylate-specific endoribonuclease (EC 4.6.1.-) (Placental protein 11) (PP11) (Protein endoU)
1_MRACI 6_ SLVLA 11_ VLCGL 16_ AWAGK 21_ IESCA 26_ SRCNE 31_ KFNRD 36_ AACQC 41_ DRRCL 46_ WHGNC 51_ CEDYE 56_ HLCTE 61_ DHKES 66_ EPLPQ 71_ LEEET 76_ EEALA 81_ SNLYS 86_ APTSC 91_ QGRCY 96_ EAFDK 101_ HHQCH 106_ CNARC 111_ QEFGN 116_ CCKDF 121_ ESLCS 126_ DHEVS 131_ HSSDA 136_ ITKEE 141_ IQSIS 146_ EKIYR 151_ ADTNK 156_ AQKED 161_ IVLNS 166_ QNCIS 171_ PSETR 176_ NQVDR 181_ CPKPL 186_ FTYVN 191_ EKLFS 196_ KPTYA 201_ AFINL 206_ LNNYQ 211_ RATGH 216_ GEHFS 221_ AQELA 226_ EQDAF 231_ LREIM 236_ KTAVM 241_ KELYS 246_ FLHHQ 251_ NRYGS 256_ EQEFV 261_ DDLKN 266_ MWFGL 271_ YSRGN 276_ EEGDS 281_ SGFEH 286_ VFSGE 291_ VKKGK 296_ VTGFH 301_ NWIRF 306_ YLEEK 311_ EGLVD 316_ YYSHI 321_ YDGPW 326_ DSYPD 331_ VLAMQ 336_ FNWDG 341_ YYKEV 346_ GSAFI 351_ GSSPE 356_ FEFAL 361_ YSLCF 366_ IARPG 371_ KVCQL 376_ SLGGY 381_ PLAVR 386_ TYTWD 391_ KSTYG 396_ NGKKY 401_IATAY
1: Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites (PubMed:18936097). Targets mRNAs to regulate their expression (PubMed:37803019)