Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A)
1_MENQE 6_ KASIA 11_ GHMFD 16_ VVVIG 21_ GGISG 26_ LSAAK 31_ LLTEY 36_ GVSVL 41_ VLEAR 46_ DRVGG 51_ RTYTI 56_ RNEHV 61_ DYVDV 66_ GGAYV 71_ GPTQN 76_ RILRL 81_ SKELG 86_ IETYK 91_ VNVSE 96_ RLVQY 101_ VKGKT 106_ YPFRG 111_ AFPPV 116_ WNPIA 121_ YLDYN 126_ NLWRT 131_ IDNMG 136_ KEIPT 141_ DAPWE 146_ AQHAD 151_ KWDKM 156_ TMKEL 161_ IDKIC 166_ WTKTA 171_ RRFAY 176_ LFVNI 181_ NVTSE 186_ PHEVS 191_ ALWFL 196_ WYVKQ 201_ CGGTT 206_ RIFSV 211_ TNGGQ 216_ ERKFV 221_ GGSGQ 226_ VSERI 231_ MDLLG 236_ DQVKL 241_ NHPVT 246_ HVDQS 251_ SDNII 256_ IETLN 261_ HEHYE 266_ CKYVI 271_ NAIPP 276_ TLTAK 281_ IHFRP 286_ ELPAE 291_ RNQLI 296_ QRLPM 301_ GAVIK 306_ CMMYY 311_ KEAFW 316_ KKKDY 321_ CGCMI 326_ IEDED 331_ APISI 336_ TLDDT 341_ KPDGS 346_ LPAIM 351_ GFILA 356_ RKADR 361_ LAKLH 366_ KEIRK 371_ KKICE 376_ LYAKV 381_ LGSQE 386_ ALHPV 391_ HYEEK 396_ NWCEE 401_ QYSGG 406_ CYTAY 411_ FPPGI 416_ MTQYG 421_ RVIRQ 426_ PVGRI 431_ FFAGT 436_ ETATK 441_ WSGYM 446_ EGAVE 451_ AGERA 456_ AREVL 461_ NGLGK 466_ VTEKD 471_ IWVQE 476_ PESKD 481_ VPAVE 486_ ITHTF 491_ WERNL 496_ PSVSG 501_ LLKII 506_ GFSTS 511_ VTALG 516_ FVLYK 521_YKLLP
1: Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:18391214, PubMed:20493079, PubMed:24169519, PubMed:8316221). Preferentially oxidizes serotonin (PubMed:20493079, PubMed:24169519). Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline (By similarity)