Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
1_MRAND 6_ ALQVL 11_ GLLFS 16_ LARGS 21_ EVGNS 26_ QAVCP 31_ GTLNG 36_ LSVTG 41_ DAENQ 46_ YQTLY 51_ KLYER 56_ CEVVM 61_ GNLEI 66_ VLTGH 71_ NADLS 76_ FLQWI 81_ REVTG 86_ YVLVA 91_ MNEFS 96_ TLPLP 101_ NLRVV 106_ RGTQV 111_ YDGKF 116_ AIFVM 121_ LNYNT 126_ NSSHA 131_ LRQLR 136_ LTQLT 141_ EILSG 146_ GVYIE 151_ KNDKL 156_ CHMDT 161_ IDWRD 166_ IVRDR 171_ DAEIV 176_ VKDNG 181_ RSCPP 186_ CHEVC 191_ KGRCW 196_ GPGSE 201_ DCQTL 206_ TKTIC 211_ APQCN 216_ GHCFG 221_ PNPNQ 226_ CCHDE 231_ CAGGC 236_ SGPQD 241_ TDCFA 246_ CRHFN 251_ DSGAC 256_ VPRCP 261_ QPLVY 266_ NKLTF 271_ QLEPN 276_ PHTKY 281_ QYGGV 286_ CVASC 291_ PHNFV 296_ VDQTS 301_ CVRAC 306_ PPDKM 311_ EVDKN 316_ GLKMC 321_ EPCGG 326_ LCPKA 331_ CEGTG 336_ SGSRF 341_ QTVDS 346_ SNIDG 351_ FVNCT 356_ KILGN 361_ LDFLI 366_ TGLNG 371_ DPWHK 376_ IPALD 381_ PEKLN 386_ VFRTV 391_ REITG 396_ YLNIQ 401_ SWPPH 406_ MHNFS 411_ VFSNL 416_ TTIGG 421_ RSLYN 426_ RGFSL 431_ LIMKN 436_ LNVTS 441_ LGFRS 446_ LKEIS 451_ AGRIY 456_ ISANR 461_ QLCYH 466_ HSLNW 471_ TKVLR 476_ GPTEE 481_ RLDIK 486_ HNRPR 491_ RDCVA 496_ EGKVC 501_ DPLCS 506_ SGGCW 511_ GPGPG 516_ QCLSC 521_ RNYSR 526_ GGVCV 531_ THCNF 536_ LNGEP 541_ REFAH 546_ EAECF 551_ SCHPE 556_ CQPME 561_ GTATC 566_ NGSGS 571_ DTCAQ 576_ CAHFR 581_ DGPHC 586_ VSSCP 591_ HGVLG 596_ AKGPI 601_ YKYPD 606_ VQNEC 611_ RPCHE 616_ NCTQG 621_ CKGPE 626_ LQDCL 631_ GQTLV 636_ LIGKT 641_ HLTMA 646_ LTVIA 651_ GLVVI 656_ FMMLG 661_ GTFLY 666_ WRGRR 671_ IQNKR 676_ AMRRY 681_ LERGE 686_ SIEPL 691_ DPSEK 696_ ANKVL 701_ ARIFK 706_ ETELR 711_ KLKVL 716_ GSGVF 721_ GTVHK 726_ GVWIP 731_ EGESI 736_ KIPVC 741_ IKVIE 746_ DKSGR 751_ QSFQA 756_ VTDHM 761_ LAIGS 766_ LDHAH 771_ IVRLL 776_ GLCPG 781_ SSLQL 786_ VTQYL 791_ PLGSL 796_ LDHVR 801_ QHRGA 806_ LGPQL 811_ LLNWG 816_ VQIAK 821_ GMYYL 826_ EEHGM 831_ VHRNL 836_ AARNV 841_ LLKSP 846_ SQVQV 851_ ADFGV 856_ ADLLP 861_ PDDKQ 866_ LLYSE 871_ AKTPI 876_ KWMAL 881_ ESIHF 886_ GKYTH 891_ QSDVW 896_ SYGVT 901_ VWELM 906_ TFGAE 911_ PYAGL 916_ RLAEV 921_ PDLLE 926_ KGERL 931_ AQPQI 936_ CTIDV 941_ YMVMV 946_ KCWMI 951_ DENIR 956_ PTFKE 961_ LANEF 966_ TRMAR 971_ DPPRY 976_ LVIKR 981_ ESGPG 986_ IAPGP 991_ EPHGL 996_ TNKKL 1001_ EEVEL 1006_ EPELD 1011_ LDLDL 1016_ EAEED 1021_ NLATT 1026_ TLGSA 1031_ LSLPV 1036_ GTLNR 1041_ PRGSQ 1046_ SLLSP 1051_ SSGYM 1056_ PMNQG 1061_ NLGES 1066_ CQESA 1071_ VSGSS 1076_ ERCPR 1081_ PVSLH 1086_ PMPRG 1091_ CLASE 1096_ SSEGH 1101_ VTGSE 1106_ AELQE 1111_ KVSMC 1116_ RSRSR 1121_ SRSPR 1126_ PRGDS 1131_ AYHSQ 1136_ RHSLL 1141_ TPVTP 1146_ LSPPG 1151_ LEEED 1156_ VNGYV 1161_ MPDTH 1166_ LKGTP 1171_ SSREG 1176_ TLSSV 1181_ GLSSV 1186_ LGTEE 1191_ EDEDE 1196_ EYEYM 1201_ NRRRR 1206_ HSPPH 1211_ PPRPS 1216_ SLEEL 1221_ GYEYM 1226_ DVGSD 1231_ LSASL 1236_ GSTQS 1241_ CPLHP 1246_ VPIMP 1251_ TAGTT 1256_ PDEDY 1261_ EYMNR 1266_ QRDGG 1271_ GPGGD 1276_ YAAMG 1281_ ACPAS 1286_ EQGYE 1291_ EMRAF 1296_ QGPGH 1301_ QAPHV 1306_ HYARL 1311_ KTLRS 1316_ LEATD 1321_ SAFDN 1326_ PDYWH 1331_ SRLFP 1336_KANAQ
1: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). Involved in the regulation of myeloid cell differentiation (PubMed:27416908)