CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
1_MPVKG 6_ GTKCI 11_ KYLLF 16_ GFNFI 21_ FWLAG 26_ IAVLA 31_ IGLWL 36_ RFDSQ 41_ TKSIF 46_ EQETN 51_ NNNSS 56_ FYTGV 61_ YILIG 66_ AGALM 71_ MLVGF 76_ LGCCG 81_ AVQES 86_ QCMLG 91_ LFFGF 96_ LLVIF 101_ AIEIA 106_ AAIWG 111_ YSHKD 116_ EVIKE 121_ VQEFY 126_ KDTYN 131_ KLKTK 136_ DEPQR 141_ ETLKA 146_ IHYAL 151_ NCCGL 156_ AGGVE 161_ QFISD 166_ ICPKK 171_ DVLET 176_ FTVKS 181_ CPDAI 186_ KEVFD 191_ NKFHI 196_ IGAVG 201_ IGIAV 206_ VMIFG 211_ MIFSM 216_ ILCCA 221_IRRNR
1: Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PubMed:14575715, PubMed:18541721, PubMed:8478605). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (PubMed:12796480). Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity). Acts as a receptor for PSG17 (By similarity). Involved in platelet activation and aggregation (PubMed:18541721). Regulates paranodal junction formation (By similarity). Involved in cell adhesion, cell motility and tumor metastasis (PubMed:7511626, PubMed:8478605)