Gene name: CCNO

Uniprot entry:

P22674

Protein names:

Cyclin-O

Protein sequence:

1_MVTPC 6_ PTSPS 11_ SPAAR 16_ AGRRD 21_ NDQNL 26_ RAPVK 31_ KSRRP 36_ RLRRK 41_ QPLHP 46_ LNPCP 51_ LPGDS 56_ GICDL 61_ FESPS 66_ SGSDG 71_ AESPS 76_ AARGG 81_ SPLPG 86_ PAQPV 91_ AQLDL 96_ QTFRD 101_ YGQSC 106_ YAFRK 111_ AQESH 116_ FHPRE 121_ ALARQ 126_ PQVTA 131_ ESRCK 136_ LLSWL 141_ IPVHR 146_ QFGLS 151_ FESLC 156_ LTVNT 161_ LDRFL 166_ TTTPV 171_ AADCF 176_ QLLGV 181_ TSLLI 186_ ACKQV 191_ EVHPP 196_ RVKQL 201_ LALCC 206_ GAFSR 211_ QQLCN 216_ LECIV 221_ LHKLH 226_ FTLGA 231_ PTISF 236_ FLEHF 241_ THARV 246_ EAGQA 251_ EASEA 256_ LEAQA 261_ LARGV 266_ AELSL 271_ ADYAF 276_ TSYSP 281_ SLLAI 286_ CCLAL 291_ ADRML 296_ RVSRP 301_ VDLRL 306_ GDHPE 311_ AALED 316_ CMGKL 321_ QLLVA 326_ INSTS 331_ LTHML 336_ PVQIC 341_EKCSL

Protein annotations

Protein functions:

1: Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking