Insulin-like growth factor-binding protein 4 (IBP-4) (IGF-binding protein 4) (IGFBP-4)
1_MLPLC 6_ LVAAL 11_ LLAAG 16_ PGPSL 21_ GDEAI 26_ HCPPC 31_ SEEKL 36_ ARCRP 41_ PVGCE 46_ ELVRE 51_ PGCGC 56_ CATCA 61_ LGLGM 66_ PCGVY 71_ TPRCG 76_ SGLRC 81_ YPPRG 86_ VEKPL 91_ HTLMH 96_ GQGVC 101_ MELAE 106_ IEAIQ 111_ ESLQP 116_ SDKDE 121_ GDHPN 126_ NSFSP 131_ CSAHD 136_ RRCLQ 141_ KHFAK 146_ IRDRS 151_ TSGGK 156_ MKVNG 161_ APRED 166_ ARPVP 171_ QGSCQ 176_ SELHR 181_ ALERL 186_ AASQS 191_ RTHED 196_ LYIIP 201_ IPNCD 206_ RNGNF 211_ HPKQC 216_ HPALD 221_ GQRGK 226_ CWCVD 231_ RKTGV 236_ KLPGG 241_ LEPKG 246_ ELDCH 251_QLADS
1: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors