Solute carrier family 2, facilitated glucose transporter member 5 (Fructose transporter) (Glucose transporter type 5, small intestine) (GLUT-5)
1_MEQQD 6_ QSMKE 11_ GRLTL 16_ VLALA 21_ TLIAA 26_ FGSSF 31_ QYGYN 36_ VAAVN 41_ SPALL 46_ MQQFY 51_ NETYY 56_ GRTGE 61_ FMEDF 66_ PLTLL 71_ WSVTV 76_ SMFPF 81_ GGFIG 86_ SLLVG 91_ PLVNK 96_ FGRKG 101_ ALLFN 106_ NIFSI 111_ VPAIL 116_ MGCSR 121_ VATSF 126_ ELIII 131_ SRLLV 136_ GICAG 141_ VSSNV 146_ VPMYL 151_ GELAP 156_ KNLRG 161_ ALGVV 166_ PQLFI 171_ TVGIL 176_ VAQIF 181_ GLRNL 186_ LANVD 191_ GWPIL 196_ LGLTG 201_ VPAAL 206_ QLLLL 211_ PFFPE 216_ SPRYL 221_ LIQKK 226_ DEAAA 231_ KKALQ 236_ TLRGW 241_ DSVDR 246_ EVAEI 251_ RQEDE 256_ AEKAA 261_ GFISV 266_ LKLFR 271_ MRSLR 276_ WQLLS 281_ IIVLM 286_ GGQQL 291_ SGVNA 296_ IYYYA 301_ DQIYL 306_ SAGVP 311_ EEHVQ 316_ YVTAG 321_ TGAVN 326_ VVMTF 331_ CAVFV 336_ VELLG 341_ RRLLL 346_ LLGFS 351_ ICLIA 356_ CCVLT 361_ AALAL 366_ QDTVS 371_ WMPYI 376_ SIVCV 381_ ISYVI 386_ GHALG 391_ PSPIP 396_ ALLIT 401_ EIFLQ 406_ SSRPS 411_ AFMVG 416_ GSVHW 421_ LSNFT 426_ VGLIF 431_ PFIQE 436_ GLGPY 441_ SFIVF 446_ AVICL 451_ LTTIY 456_ IFLIV 461_ PETKA 466_ KTFIE 471_ INQIF 476_ TKMNK 481_ VSEVY 486_ PEKEE 491_ LKELP 496_PVTSE
1: Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed:16186102, PubMed:17710649, PubMed:28083649, PubMed:29548810, PubMed:8333543). Can mediate the uptake of 2-deoxyglucose, but with low efficiency (PubMed:1695905). Essential for fructose uptake in the small intestine (By similarity). Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (By similarity). Required for the development of high blood pressure in response to high dietary fructose intake (By similarity)