Gene name: FECH

Uniprot entry:

P22830

Protein names:

Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)

Protein sequence:

1_MRSLG 6_ ANMAA 11_ ALRAA 16_ GVLLR 21_ DPLAS 26_ SSWRV 31_ CQPWR 36_ WKSGA 41_ AAAAV 46_ TTETA 51_ QHAQG 56_ AKPQV 61_ QPQKR 66_ KPKTG 71_ ILMLN 76_ MGGPE 81_ TLGDV 86_ HDFLL 91_ RLFLD 96_ RDLMT 101_ LPIQN 106_ KLAPF 111_ IAKRR 116_ TPKIQ 121_ EQYRR 126_ IGGGS 131_ PIKIW 136_ TSKQG 141_ EGMVK 146_ LLDEL 151_ SPNTA 156_ PHKYY 161_ IGFRY 166_ VHPLT 171_ EEAIE 176_ EMERD 181_ GLERA 186_ IAFTQ 191_ YPQYS 196_ CSTTG 201_ SSLNA 206_ IYRYY 211_ NQVGR 216_ KPTMK 221_ WSTID 226_ RWPTH 231_ HLLIQ 236_ CFADH 241_ ILKEL 246_ DHFPL 251_ EKRSE 256_ VVILF 261_ SAHSL 266_ PMSVV 271_ NRGDP 276_ YPQEV 281_ SATVQ 286_ KVMER 291_ LEYCN 296_ PYRLV 301_ WQSKV 306_ GPMPW 311_ LGPQT 316_ DESIK 321_ GLCER 326_ GRKNI 331_ LLVPI 336_ AFTSD 341_ HIETL 346_ YELDI 351_ EYSQV 356_ LAKEC 361_ GVENI 366_ RRAES 371_ LNGNP 376_ LFSKA 381_ LADLV 386_ HSHIQ 391_ SNELC 396_ SKQLT 401_ LSCPL 406_ CVNPV 411_ CRETK 416_SFFTS

Protein annotations

Protein functions:

1: Catalyzes the ferrous insertion into protoporphyrin IX and participates in the terminal step in the heme biosynthetic pathway