Fibulin-1 (FIBL-1)
1_MERAA 6_ PSRRV 11_ PLPLL 16_ LLGGL 21_ ALLAA 26_ GVDAD 31_ VLLEA 36_ CCADG 41_ HRMAT 46_ HQKDC 51_ SLPYA 56_ TESKE 61_ CRMVQ 66_ EQCCH 71_ SQLEE 76_ LHCAT 81_ GISLA 86_ NEQDR 91_ CATPH 96_ GDNAS 101_ LEATF 106_ VKRCC 111_ HCCLL 116_ GRAAQ 121_ AQGQS 126_ CEYSL 131_ MVGYQ 136_ CGQVF 141_ QACCV 146_ KSQET 151_ GDLDV 156_ GGLQE 161_ TDKII 166_ EVEEE 171_ QEDPY 176_ LNDRC 181_ RGGGP 186_ CKQQC 191_ RDTGD 196_ EVVCS 201_ CFVGY 206_ QLLSD 211_ GVSCE 216_ DVNEC 221_ ITGSH 226_ SCRLG 231_ ESCIN 236_ TVGSF 241_ RCQRD 246_ SSCGT 251_ GYELT 256_ EDNSC 261_ KDIDE 266_ CESGI 271_ HNCLP 276_ DFICQ 281_ NTLGS 286_ FRCRP 291_ KLQCK 296_ SGFIQ 301_ DALGN 306_ CIDIN 311_ ECLSI 316_ SAPCP 321_ IGHTC 326_ INTEG 331_ SYTCQ 336_ KNVPN 341_ CGRGY 346_ HLNEE 351_ GTRCV 356_ DVDEC 361_ APPAE 366_ PCGKG 371_ HRCVN 376_ SPGSF 381_ RCECK 386_ TGYYF 391_ DGISR 396_ MCVDV 401_ NECQR 406_ YPGRL 411_ CGHKC 416_ ENTLG 421_ SYLCS 426_ CSVGF 431_ RLSVD 436_ GRSCE 441_ DINEC 446_ SSSPC 451_ SQECA 456_ NVYGS 461_ YQCYC 466_ RRGYQ 471_ LSDVD 476_ GVTCE 481_ DIDEC 486_ ALPTG 491_ GHICS 496_ YRCIN 501_ IPGSF 506_ QCSCP 511_ SSGYR 516_ LAPNG 521_ RNCQD 526_ IDECV 531_ TGIHN 536_ CSINE 541_ TCFNI 546_ QGGFR 551_ CLAFE 556_ CPENY 561_ RRSAA 566_ TLQQE 571_ KTDTV 576_ RCIKS 581_ CRPND 586_ VTCVF 591_ DPVHT 596_ ISHTV 601_ ISLPT 606_ FREFT 611_ RPEEI 616_ IFLRA 621_ ITPPH 626_ PASQA 631_ NIIFD 636_ ITEGN 641_ LRDSF 646_ DIIKR 651_ YMDGM 656_ TVGVV 661_ RQVRP 666_ IVGPF 671_ HAVLK 676_ LEMNY 681_ VVGGV 686_ VSHRN 691_ VVNVH 696_IFVSE
1: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP