C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]
1_MHLSQ 6_ LLACA 11_ LLLTL 16_ LSLRP 21_ SEAKP 26_ GAPPK 31_ VPRTP 36_ PAEEL 41_ AEPQA 46_ AGGGQ 51_ KKGDK 56_ APGGG 61_ GANLK 66_ GDRSR 71_ LLRDL 76_ RVDTK 81_ SRAAW 86_ ARLLQ 91_ EHPNA 96_ RKYKG 101_ ANKKG 106_ LSKGC 111_ FGLKL 116_ DRIGS 121_MSGLG
1: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation (By similarity). May also be vasoactive and natriuretic (PubMed:1672777). Acts by specifically binding and stimulating NPR2 to produce cGMP (PubMed:1672777, PubMed:21098034). Binds the clearance receptor NPR3 (PubMed:11533490)