Cytochrome c oxidase subunit 7A1, mitochondrial (Cytochrome c oxidase subunit VIIa-heart) (Cytochrome c oxidase subunit VIIa-H) (Cytochrome c oxidase subunit VIIa-muscle) (Cytochrome c oxidase subunit VIIa-M)
1_MQALR 6_ VSQAL 11_ IRSFS 16_ STARN 21_ RFQNR 26_ VREKQ 31_ KLFQE 36_ DNDIP 41_ LYLKG 46_ GIVDN 51_ ILYRV 56_ TMTLC 61_ LGGTV 66_ YSLYS 71_LGWAS
1: Component of the mitochondrial respiratory complex IV (CIV, also named cytochrome c oxidase complex), the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation (By similarity). The CIV complex is the component of the respiratory chain that catalyzes the reduction of oxygen to water (By similarity). Acts as an assembly factor that specifically drives the homodimerization of CIV complexes, mediating the formation of mitochondrial respiratory supercomplexes (respirasomes) containing two CIV: supercomplxes with two molecules of CIV show improved activity (By similarity). Despite being highly expressed in brown adipose tissue, not required for thermogenesis (By similarity)