Gene name: COL8A2

Uniprot entry:

P25067

Protein names:

Collagen alpha-2(VIII) chain (Endothelial collagen)

Protein sequence:

1_MLGTL 6_ TPLSS 11_ LLLLL 16_ LVLVL 21_ GCGPR 26_ ASSGG 31_ GAGGA 36_ AGYAP 41_ VKYIQ 46_ PMQKG 51_ PVGPP 56_ FREGK 61_ GQYLE 66_ MPLPL 71_ LPMDL 76_ KGEPG 81_ PPGKP 86_ GPRGP 91_ PGPPG 96_ FPGKP 101_ GMGKP 106_ GLHGQ 111_ PGPAG 116_ PPGFS 121_ RMGKA 126_ GPPGL 131_ PGKVG 136_ PPGQP 141_ GLRGE 146_ PGIRG 151_ DQGLR 156_ GPPGP 161_ PGLPG 166_ PSGIT 171_ IPGKP 176_ GAQGV 181_ PGPPG 186_ FQGEP 191_ GPQGE 196_ PGPPG 201_ DRGLK 206_ GDNGV 211_ GQPGL 216_ PGAPG 221_ QGGAP 226_ GPPGL 231_ PGPAG 236_ LGKPG 241_ LDGLP 246_ GAPGD 251_ KGESG 256_ PPGVP 261_ GPRGE 266_ PGAVG 271_ PKGPP 276_ GVDGV 281_ GVPGA 286_ AGLPG 291_ PQGPS 296_ GAKGE 301_ PGTRG 306_ PPGLI 311_ GPTGY 316_ GMPGL 321_ PGPKG 326_ DRGPA 331_ GVPGL 336_ LGDRG 341_ EPGED 346_ GEPGE 351_ QGPQG 356_ LGGPP 361_ GLPGS 366_ AGLPG 371_ RRGPP 376_ GPKGE 381_ AGPGG 386_ PPGVP 391_ GIRGD 396_ QGPSG 401_ LAGKP 406_ GVPGE 411_ RGLPG 416_ AHGPP 421_ GPTGP 426_ KGEPG 431_ FTGRP 436_ GGPGV 441_ AGALG 446_ QKGDL 451_ GLPGQ 456_ PGLRG 461_ PSGIP 466_ GLQGP 471_ AGPIG 476_ PQGLP 481_ GLKGE 486_ PGLPG 491_ PPGEG 496_ RAGEP 501_ GTAGP 506_ TGPPG 511_ VPGSP 516_ GITGP 521_ PGPPG 526_ PPGPP 531_ GAPGA 536_ FDETG 541_ IAGLH 546_ LPNGG 551_ VEGAV 556_ LGKGG 561_ KPQFG 566_ LGELS 571_ AHATP 576_ AFTAV 581_ LTSPF 586_ PASGM 591_ PVKFD 596_ RTLYN 601_ GHSGY 606_ NPATG 611_ IFTCP 616_ VGGVY 621_ YFAYH 626_ VHVKG 631_ TNVWV 636_ ALYKN 641_ NVPAT 646_ YTYDE 651_ YKKGY 656_ LDQAS 661_ GGAVL 666_ QLRPN 671_ DQVWV 676_ QMPSD 681_ QANGL 686_ YSTEY 691_ IHSSF 696_SGFLL

Protein annotations

Protein functions:

1: Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also a component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity)