Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)
1_METLC 6_ LRASF 11_ WLALV 16_ GCVIS 21_ DNPER 26_ YSTNL 31_ SNHVD 36_ DFTTF 41_ RGTEL 46_ SFLVT 51_ THQPT 56_ NLVLP 61_ SNGSM 66_ HNYCP 71_ QQTKI 76_ TSAFK 81_ YINTV 86_ ISCTI 91_ FIVGM 96_ VGNAT 101_ LLRII 106_ YQNKC 111_ MRNGP 116_ NALIA 121_ SLALG 126_ DLIYV 131_ VIDLP 136_ INVFK 141_ LLAGR 146_ WPFDH 151_ NDFGV 156_ FLCKL 161_ FPFLQ 166_ KSSVG 171_ ITVLN 176_ LCALS 181_ VDRYR 186_ AVASW 191_ SRVQG 196_ IGIPL 201_ VTAIE 206_ IVSIW 211_ ILSFI 216_ LAIPE 221_ AIGFV 226_ MVPFE 231_ YRGEQ 236_ HKTCM 241_ LNATS 246_ KFMEF 251_ YQDVK 256_ DWWLF 261_ GFYFC 266_ MPLVC 271_ TAIFY 276_ TLMTC 281_ EMLNR 286_ RNGSL 291_ RIALS 296_ EHLKQ 301_ RREVA 306_ KTVFC 311_ LVVIF 316_ ALCWF 321_ PLHLS 326_ RILKK 331_ TVYNE 336_ MDKNR 341_ CELLS 346_ FLLLM 351_ DYIGI 356_ NLATM 361_ NSCIN 366_ PIALY 371_ FVSKK 376_ FKNCF 381_ QSCLC 386_ CCCYQ 391_ SKSLM 396_ TSVPM 401_ NGTSI 406_ QWKNH 411_ DQNNH 416_ NTDRS 421_SHKDS
1: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3