Cathepsin S (EC 3.4.22.27)
1_MKRLV 6_ CVLLV 11_ CSSAV 16_ AQLHK 21_ DPTLD 26_ HHWHL 31_ WKKTY 36_ GKQYK 41_ EKNEE 46_ AVRRL 51_ IWEKN 56_ LKFVM 61_ LHNLE 66_ HSMGM 71_ HSYDL 76_ GMNHL 81_ GDMTS 86_ EEVMS 91_ LMSSL 96_ RVPSQ 101_ WQRNI 106_ TYKSN 111_ PNRIL 116_ PDSVD 121_ WREKG 126_ CVTEV 131_ KYQGS 136_ CGACW 141_ AFSAV 146_ GALEA 151_ QLKLK 156_ TGKLV 161_ SLSAQ 166_ NLVDC 171_ STEKY 176_ GNKGC 181_ NGGFM 186_ TTAFQ 191_ YIIDN 196_ KGIDS 201_ DASYP 206_ YKAMD 211_ QKCQY 216_ DSKYR 221_ AATCS 226_ KYTEL 231_ PYGRE 236_ DVLKE 241_ AVANK 246_ GPVSV 251_ GVDAR 256_ HPSFF 261_ LYRSG 266_ VYYEP 271_ SCTQN 276_ VNHGV 281_ LVVGY 286_ GDLNG 291_ KEYWL 296_ VKNSW 301_ GHNFG 306_ EEGYI 311_ RMARN 316_ KGNHC 321_ GIASF 326_PSYPE
1: Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation (PubMed:30612035). The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L