60S ribosomal protein L13 (Breast basic conserved protein 1) (Large ribosomal subunit protein eL13)
1_MAPSR 6_ NGMVL 11_ KPHFH 16_ KDWQR 21_ RVATW 26_ FNQPA 31_ RKIRR 36_ RKARQ 41_ AKARR 46_ IAPRP 51_ ASGPI 56_ RPIVR 61_ CPTVR 66_ YHTKV 71_ RAGRG 76_ FSLEE 81_ LRVAG 86_ IHKKV 91_ ARTIG 96_ ISVDP 101_ RRRNK 106_ STESL 111_ QANVQ 116_ RLKEY 121_ RSKLI 126_ LFPRK 131_ PSAPK 136_ KGDSS 141_ AEELK 146_ LATQL 151_ TGPVM 156_ PVRNV 161_ YKKEK 166_ ARVIT 171_ EEEKN 176_ FKAFA 181_ SLRMA 186_ RANAR 191_ LFGIR 196_ AKRAK 201_ EAAEQ 206_DVEKK
1: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:31630789, PubMed:32669547). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable). As part of the LSU, it is probably required for its formation and the maturation of rRNAs (PubMed:31630789). Plays a role in bone development (PubMed:31630789)