Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (K-45) (Serum aryldialkylphosphatase 1)
1_MAKLI 6_ ALTLL 11_ GMGLA 16_ LFRNH 21_ QSSYQ 26_ TRLNA 31_ LREVQ 36_ PVELP 41_ NCNLV 46_ KGIET 51_ GSEDL 56_ EILPN 61_ GLAFI 66_ SSGLK 71_ YPGIK 76_ SFNPN 81_ SPGKI 86_ LLMDL 91_ NEEDP 96_ TVLEL 101_ GITGS 106_ KFDVS 111_ SFNPH 116_ GISTF 121_ TDEDN 126_ AMYLL 131_ VVNHP 136_ DAKST 141_ VELFK 146_ FQEEE 151_ KSLLH 156_ LKTIR 161_ HKLLP 166_ NLNDI 171_ VAVGP 176_ EHFYG 181_ TNDHY 186_ FLDPY 191_ LQSWE 196_ MYLGL 201_ AWSYV 206_ VYYSP 211_ SEVRV 216_ VAEGF 221_ DFANG 226_ INISP 231_ DGKYV 236_ YIAEL 241_ LAHKI 246_ HVYEK 251_ HANWT 256_ LTPLK 261_ SLDFN 266_ TLVDN 271_ ISVDP 276_ ETGDL 281_ WVGCH 286_ PNGMK 291_ IFFYD 296_ SENPP 301_ ASEVL 306_ RIQNI 311_ LTEEP 316_ KVTQV 321_ YAENG 326_ TVLQG 331_ STVAS 336_ VYKGK 341_ LLIGT 346_VFHKA
1: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation