Gene name: ATP6V0C

Uniprot entry:

P27449

Protein names:

V-type proton ATPase 16 kDa proteolipid subunit c (V-ATPase 16 kDa proteolipid subunit c) (Vacuolar proton pump 16 kDa proteolipid subunit c)

Protein sequence:

1_MSESK 6_ SGPEY 11_ ASFFA 16_ VMGAS 21_ AAMVF 26_ SALGA 31_ AYGTA 36_ KSGTG 41_ IAAMS 46_ VMRPE 51_ QIMKS 56_ IIPVV 61_ MAGII 66_ AIYGL 71_ VVAVL 76_ IANSL 81_ NDDIS 86_ LYKSF 91_ LQLGA 96_ GLSVG 101_ LSGLA 106_ AGFAI 111_ GIVGD 116_ AGVRG 121_ TAQQP 126_ RLFVG 131_ MILIL 136_ IFAEV 141_ LGLYG 146_LIVAL

Protein annotations

Protein functions:

1: Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002, PubMed:36074901). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments, and in some cell types, it is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity)