Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
1_MEGKW 6_ LLCML 11_ LVLGT 16_ AIVEA 21_ HDGHD 26_ DDVID 31_ IEDDL 36_ DDVIE 41_ EVEDS 46_ KPDTT 51_ APPSS 56_ PKVTY 61_ KAPVP 66_ TGEVY 71_ FADSF 76_ DRGTL 81_ SGWIL 86_ SKAKK 91_ DDTDD 96_ EIAKY 101_ DGKWE 106_ VEEMK 111_ ESKLP 116_ GDKGL 121_ VLMSR 126_ AKHHA 131_ ISAKL 136_ NKPFL 141_ FDTKP 146_ LIVQY 151_ EVNFQ 156_ NGIEC 161_ GGAYV 166_ KLLSK 171_ TPELN 176_ LDQFH 181_ DKTPY 186_ TIMFG 191_ PDKCG 196_ EDYKL 201_ HFIFR 206_ HKNPK 211_ TGIYE 216_ EKHAK 221_ RPDAD 226_ LKTYF 231_ TDKKT 236_ HLYTL 241_ ILNPD 246_ NSFEI 251_ LVDQS 256_ VVNSG 261_ NLLND 266_ MTPPV 271_ NPSRE 276_ IEDPE 281_ DRKPE 286_ DWDER 291_ PKIPD 296_ PEAVK 301_ PDDWD 306_ EDAPA 311_ KIPDE 316_ EATKP 321_ EGWLD 326_ DEPEY 331_ VPDPD 336_ AEKPE 341_ DWDED 346_ MDGEW 351_ EAPQI 356_ ANPRC 361_ ESAPG 366_ CGVWQ 371_ RPVID 376_ NPNYK 381_ GKWKP 386_ PMIDN 391_ PSYQG 396_ IWKPR 401_ KIPNP 406_ DFFED 411_ LEPFR 416_ MTPFS 421_ AIGLE 426_ LWSMT 431_ SDIFF 436_ DNFII 441_ CADRR 446_ IVDDW 451_ ANDGW 456_ GLKKA 461_ ADGAA 466_ EPGVV 471_ GQMIE 476_ AAEER 481_ PWLWV 486_ VYILT 491_ VALPV 496_ FLVIL 501_ FCCSG 506_ KKQTS 511_ GMEYK 516_ KTDAP 521_ QPDVK 526_ EEEEE 531_ KEEEK 536_ DKGDE 541_ EEEGE 546_ EKLEE 551_ KQKSD 556_ AEEDG 561_ GTVSQ 566_ EEEDR 571_ KPKAE 576_ EDEIL 581_ NRSPR 586_NRKPR
1: Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse