Pituitary-specific positive transcription factor 1 (PIT-1) (Growth hormone factor 1) (GHF-1)
1_MSCQA 6_ FTSAD 11_ TFIPL 16_ NSDAS 21_ ATLPL 26_ IMHHS 31_ AAECL 36_ PVSNH 41_ ATNVM 46_ STATG 51_ LHYSV 56_ PSCHY 61_ GNQPS 66_ TYGVM 71_ AGSLT 76_ PCLYK 81_ FPDHT 86_ LSHGF 91_ PPIHQ 96_ PLLAE 101_ DPTAA 106_ DFKQE 111_ LRRKS 116_ KLVEE 121_ PIDMD 126_ SPEIR 131_ ELEKF 136_ ANEFK 141_ VRRIK 146_ LGYTQ 151_ TNVGE 156_ ALAAV 161_ HGSEF 166_ SQTTI 171_ CRFEN 176_ LQLSF 181_ KNACK 186_ LKAIL 191_ SKWLE 196_ EAEQV 201_ GALYN 206_ EKVGA 211_ NERKR 216_ KRRTT 221_ ISIAA 226_ KDALE 231_ RHFGE 236_ QNKPS 241_ SQEIM 246_ RMAEE 251_ LNLEK 256_ EVVRV 261_ WFCNR 266_ RQREK 271_ RVKTS 276_ LNQSL 281_ FSISK 286_EHLEC
1: Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Specifically binds to the consensus sequence 5'-TAAAT-3'. Activates growth hormone and prolactin genes (PubMed:22010633, PubMed:26612202)