NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD)
1_MLRIP 6_ VRKAL 11_ VGLSK 16_ SPKGC 21_ VRTTA 26_ TAASN 31_ LIEVF 36_ VDGQS 41_ VMVEP 46_ GTTVL 51_ QACEK 56_ VGMQI 61_ PRFCY 66_ HERLS 71_ VAGNC 76_ RMCLV 81_ EIEKA 86_ PKVVA 91_ ACAMP 96_ VMKGW 101_ NILTN 106_ SEKSK 111_ KAREG 116_ VMEFL 121_ LANHP 126_ LDCPI 131_ CDQGG 136_ ECDLQ 141_ DQSMM 146_ FGNDR 151_ SRFLE 156_ GKRAV 161_ EDKNI 166_ GPLVK 171_ TIMTR 176_ CIQCT 181_ RCIRF 186_ ASEIA 191_ GVDDL 196_ GTTGR 201_ GNDMQ 206_ VGTYI 211_ EKMFM 216_ SELSG 221_ NIIDI 226_ CPVGA 231_ LTSKP 236_ YAFTA 241_ RPWET 246_ RKTES 251_ IDVMD 256_ AVGSN 261_ IVVST 266_ RTGEV 271_ MRILP 276_ RMHED 281_ INEEW 286_ ISDKT 291_ RFAYD 296_ GLKRQ 301_ RLTEP 306_ MVRNE 311_ KGLLT 316_ YTSWE 321_ DALSR 326_ VAGML 331_ QSFQG 336_ KDVAA 341_ IAGGL 346_ VDAEA 351_ LVALK 356_ DLLNR 361_ VDSDT 366_ LCTEE 371_ VFPTA 376_ GAGTD 381_ LRSNY 386_ LLNTT 391_ IAGVE 396_ EADVV 401_ LLVGT 406_ NPRFE 411_ APLFN 416_ ARIRK 421_ SWLHN 426_ DLKVA 431_ LIGSP 436_ VDLTY 441_ TYDHL 446_ GDSPK 451_ ILQDI 456_ ASGSH 461_ PFSQV 466_ LKEAK 471_ KPMVV 476_ LGSSA 481_ LQRND 486_ GAAIL 491_ AAVSS 496_ IAQKI 501_ RMTSG 506_ VTGDW 511_ KVMNI 516_ LHRIA 521_ SQVAA 526_ LDLGY 531_ KPGVE 536_ AIRKN 541_ PPKVL 546_ FLLGA 551_ DGGCI 556_ TRQDL 561_ PKDCF 566_ IIYQG 571_ HHGDV 576_ GAPIA 581_ DVILP 586_ GAAYT 591_ EKSAT 596_ YVNTE 601_ GRAQQ 606_ TKVAV 611_ TPPGL 616_ AREDW 621_ KIIRA 626_ LSEIA 631_ GMTLP 636_ YDTLD 641_ QVRNR 646_ LEEVS 651_ PNLVR 656_ YDDIE 661_ GANYF 666_ QQANE 671_ LSKLV 676_ NQQLL 681_ ADPLV 686_ PPQLT 691_ IKDFY 696_ MTDSI 701_ SRASQ 706_ TMAKC 711_ VKAVT 716_ EGAQA 721_VEEPS
1: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:31557978). Essential for catalysing the entry and efficient transfer of electrons within complex I (PubMed:31557978). Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:30879903, PubMed:31557978)