CCN family member 2 (Cellular communication network factor 2) (Connective tissue growth factor) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8)
1_MTAAS 6_ MGPVR 11_ VAFVV 16_ LLALC 21_ SRPAV 26_ GQNCS 31_ GPCRC 36_ PDEPA 41_ PRCPA 46_ GVSLV 51_ LDGCG 56_ CCRVC 61_ AKQLG 66_ ELCTE 71_ RDPCD 76_ PHKGL 81_ FCHFG 86_ SPANR 91_ KIGVC 96_ TAKDG 101_ APCIF 106_ GGTVY 111_ RSGES 116_ FQSSC 121_ KYQCT 126_ CLDGA 131_ VGCMP 136_ LCSMD 141_ VRLPS 146_ PDCPF 151_ PRRVK 156_ LPGKC 161_ CEEWV 166_ CDEPK 171_ DQTVV 176_ GPALA 181_ AYRLE 186_ DTFGP 191_ DPTMI 196_ RANCL 201_ VQTTE 206_ WSACS 211_ KTCGM 216_ GISTR 221_ VTNDN 226_ ASCRL 231_ EKQSR 236_ LCMVR 241_ PCEAD 246_ LEENI 251_ KKGKK 256_ CIRTP 261_ KISKP 266_ IKFEL 271_ SGCTS 276_ MKTYR 281_ AKFCG 286_ VCTDG 291_ RCCTP 296_ HRTTT 301_ LPVEF 306_ KCPDG 311_ EVMKK 316_ NMMFI 321_ KTCAC 326_ HYNCP 331_ GDNDI 336_ FESLY 341_YRKMY
1: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis (PubMed:39414788). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis