ATP synthase subunit delta, mitochondrial (ATP synthase F1 subunit delta) (F-ATPase delta subunit)
1_MLPAA 6_ LLRRP 11_ GLGRL 16_ VRHAR 21_ AYAEA 26_ AAAPA 31_ AASGP 36_ NQMSF 41_ TFASP 46_ TQVFF 51_ NGANV 56_ RQVDV 61_ PTLTG 66_ AFGIL 71_ AAHVP 76_ TLQVL 81_ RPGLV 86_ VVHAE 91_ DGTTS 96_ KYFVS 101_ SGSIA 106_ VNADS 111_ SVQLL 116_ AEEAV 121_ TLDML 126_ DLGAA 131_ KANLE 136_ KAQAE 141_ LVGTA 146_ DEATR 151_ AEIQI 156_ RIEAN 161_EALVK
1: Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable) (PubMed:37244256). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). With the central stalk subunit gamma, is essential for the biogenesis of F(1) catalytic part of the ATP synthase complex namely in the formation of F1 assembly intermediate (PubMed:29499186)