Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
1_MTVLQ 6_ EPVQA 11_ AIWQA 16_ LNHYA 21_ YRDAV 26_ FLAER 31_ LYAEV 36_ HSEEA 41_ LFLLA 46_ TCYYR 51_ SGKAY 56_ KAYRL 61_ LKGHS 66_ CTTPQ 71_ CKYLL 76_ AKCCV 81_ DLSKL 86_ AEGEQ 91_ ILSGG 96_ VFNKQ 101_ KSHDD 106_ IVTEF 111_ GDSAC 116_ FTLSL 121_ LGHVY 126_ CKTDR 131_ LAKGS 136_ ECYQK 141_ SLSLN 146_ PFLWS 151_ PFESL 156_ CEIGE 161_ KPDPD 166_ QTFKF 171_ TSLQN 176_ FSNCL 181_ PNSCT 186_ TQVPN 191_ HSLSH 196_ RQPET 201_ VLTET 206_ PQDTI 211_ ELNRL 216_ NLESS 221_ NSKYS 226_ LNTDS 231_ SVSYI 236_ DSAVI 241_ SPDTV 246_ PLGTG 251_ TSILS 256_ KQVQN 261_ KPKTG 266_ RSLLG 271_ GPAAL 276_ SPLTP 281_ SFGIL 286_ PLETP 291_ SPGDG 296_ SYLQN 301_ YTNTP 306_ PVIDV 311_ PSTGA 316_ PSKKS 321_ VARIG 326_ QTGTK 331_ SVFSQ 336_ SGNSR 341_ EVTPI 346_ LAQTQ 351_ SSGPQ 356_ TSTTP 361_ QVLSP 366_ TITSP 371_ PNALP 376_ RRSSR 381_ LFTSD 386_ SSTTK 391_ ENSKK 396_ LKMKF 401_ PPKIP 406_ NRKTK 411_ SKTNK 416_ GGITQ 421_ PNIND 426_ SLEIT 431_ KLDSS 436_ IISEG 441_ KISTI 446_ TPQIQ 451_ AFNLQ 456_ KAAAE 461_ GLMSL 466_ LREMG 471_ KGYLA 476_ LCSYN 481_ CKEAI 486_ NILSH 491_ LPSHH 496_ YNTGW 501_ VLCQI 506_ GRAYF 511_ ELSEY 516_ MQAER 521_ IFSEV 526_ RRIEN 531_ YRVEG 536_ MEIYS 541_ TTLWH 546_ LQKDV 551_ ALSVL 556_ SKDLT 561_ DMDKN 566_ SPEAW 571_ CAAGN 576_ CFSLQ 581_ REHDI 586_ AIKFF 591_ QRAIQ 596_ VDPNY 601_ AYAYT 606_ LLGHE 611_ FVLTE 616_ ELDKA 621_ LACFR 626_ NAIRV 631_ NPRHY 636_ NAWYG 641_ LGMIY 646_ YKQEK 651_ FSLAE 656_ MHFQK 661_ ALDIN 666_ PQSSV 671_ LLCHI 676_ GVVQH 681_ ALKKS 686_ EKALD 691_ TLNKA 696_ IVIDP 701_ KNPLC 706_ KFHRA 711_ SVLFA 716_ NEKYK 721_ SALQE 726_ LEELK 731_ QIVPK 736_ ESLVY 741_ FLIGK 746_ VYKKL 751_ GQTHL 756_ ALMNF 761_ SWAMD 766_ LDPKG 771_ ANNQI 776_ KEAID 781_ KRYLP 786_ DDEEP 791_ ITQEE 796_ QIMGT 801_ DESQE 806_ SSMTD 811_ ADDTQ 816_LHAAE
1: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed:18485873). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (PubMed:18485873). The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins (PubMed:29033132)