Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (HsNMT1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1) (Protein-lysine myristoyltransferase NMT1) (EC 2.3.1.-)
1_MADES 6_ ETAVK 11_ PPAPP 16_ LPQMM 21_ EGNGN 26_ GHEHC 31_ SDCEN 36_ EEDNS 41_ YNRGG 46_ LSPAN 51_ DTGAK 56_ KKKKK 61_ QKKKK 66_ EKGSE 71_ TDSAQ 76_ DQPVK 81_ MNSLP 86_ AERIQ 91_ EIQKA 96_ IELFS 101_ VGQGP 106_ AKTME 111_ EASKR 116_ SYQFW 121_ DTQPV 126_ PKLGE 131_ VVNTH 136_ GPVEP 141_ DKDNI 146_ RQEPY 151_ TLPQG 156_ FTWDA 161_ LDLGD 166_ RGVLK 171_ ELYTL 176_ LNENY 181_ VEDDD 186_ NMFRF 191_ DYSPE 196_ FLLWA 201_ LRPPG 206_ WLPQW 211_ HCGVR 216_ VVSSR 221_ KLVGF 226_ ISAIP 231_ ANIHI 236_ YDTEK 241_ KMVEI 246_ NFLCV 251_ HKKLR 256_ SKRVA 261_ PVLIR 266_ EITRR 271_ VHLEG 276_ IFQAV 281_ YTAGV 286_ VLPKP 291_ VGTCR 296_ YWHRS 301_ LNPRK 306_ LIEVK 311_ FSHLS 316_ RNMTM 321_ QRTMK 326_ LYRLP 331_ ETPKT 336_ AGLRP 341_ METKD 346_ IPVVH 351_ QLLTR 356_ YLKQF 361_ HLTPV 366_ MSQEE 371_ VEHWF 376_ YPQEN 381_ IIDTF 386_ VVENA 391_ NGEVT 396_ DFLSF 401_ YTLPS 406_ TIMNH 411_ PTHKS 416_ LKAAY 421_ SFYNV 426_ HTQTP 431_ LLDLM 436_ SDALV 441_ LAKMK 446_ GFDVF 451_ NALDL 456_ MENKT 461_ FLEKL 466_ KFGIG 471_ DGNLQ 476_ YYLYN 481_ WKCPS 486_ MGAEK 491_VGLVL
1: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins (PubMed:22865860, PubMed:25255805, PubMed:32686708, PubMed:34999170, PubMed:9353336, PubMed:9506952). Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3' (PubMed:32103017, PubMed:32111831). Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle (PubMed:32103017)