Heme oxygenase 2 (HO-2) (EC 1.14.14.18) [Cleaved into: Heme oxygenase 2 soluble form]
1_MSAEV 6_ ETSEG 11_ VDESE 16_ KKNSG 21_ ALEKE 26_ NQMRM 31_ ADLSE 36_ LLKEG 41_ TKEAH 46_ DRAEN 51_ TQFVK 56_ DFLKG 61_ NIKKE 66_ LFKLA 71_ TTALY 76_ FTYSA 81_ LEEEM 86_ ERNKD 91_ HPAFA 96_ PLYFP 101_ MELHR 106_ KEALT 111_ KDMEY 116_ FFGEN 121_ WEEQV 126_ QCPKA 131_ AQKYV 136_ ERIHY 141_ IGQNE 146_ PELLV 151_ AHAYT 156_ RYMGD 161_ LSGGQ 166_ VLKKV 171_ AQRAL 176_ KLPST 181_ GEGTQ 186_ FYLFE 191_ NVDNA 196_ QQFKQ 201_ LYRAR 206_ MNALD 211_ LNMKT 216_ KERIV 221_ EEANK 226_ AFEYN 231_ MQIFN 236_ ELDQA 241_ GSTLA 246_ RETLE 251_ DGFPV 256_ HDGKG 261_ DMRKC 266_ PFYAA 271_ EQDKG 276_ ALEGS 281_ SCPFR 286_ TAMAV 291_ LRKPS 296_ LQFIL 301_ AAGVA 306_ LAAGL 311_LAWYY
1: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron
2: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron