Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)
1_MAPPW 6_ VPAMG 11_ FTLAP 16_ SLGCF 21_ VGSRF 26_ VHGEG 31_ LRWYA 36_ GLQKP 41_ SWHPP 46_ HWVLG 51_ PVWGT 56_ LYSAM 61_ GYGSY 66_ LVWKE 71_ LGGFT 76_ EKAVV 81_ PLGLY 86_ TGQLA 91_ LNWAW 96_ PPIFF 101_ GARQM 106_ GWALV 111_ DLLLV 116_ SGAAA 121_ ATTVA 126_ WYQVS 131_ PLAAR 136_ LLYPY 141_ LAWLA 146_ FTTTL 151_ NYCVW 156_ RDNHG 161_WRGGR
1: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678)