Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase)
1_MAAGG 6_ DHGSP 11_ DSYRS 16_ PLASR 21_ YASPE 26_ MCFVF 31_ SDRYK 36_ FRTWR 41_ QLWLW 46_ LAEAE 51_ QTLGL 56_ PITDE 61_ QIQEM 66_ KSNLE 71_ NIDFK 76_ MAAEE 81_ EKRLR 86_ HDVMA 91_ HVHTF 96_ GHCCP 101_ KAAGI 106_ IHLGA 111_ TSCYV 116_ GDNTD 121_ LIILR 126_ NALDL 131_ LLPKL 136_ ARVIS 141_ RLADF 146_ AKERA 151_ SLPTL 156_ GFTHF 161_ QPAQL 166_ TTVGK 171_ RCCLW 176_ IQDLC 181_ MDLQN 186_ LKRVR 191_ DDLRF 196_ RGVKG 201_ TTGTQ 206_ ASFLQ 211_ LFEGD 216_ DHKVE 221_ QLDKM 226_ VTEKA 231_ GFKRA 236_ FIITG 241_ QTYTR 246_ KVDIE 251_ VLSVL 256_ ASLGA 261_ SVHKI 266_ CTDIR 271_ LLANL 276_ KEMEE 281_ PFEKQ 286_ QIGSS 291_ AMPYK 296_ RNPMR 301_ SERCC 306_ SLARH 311_ LMTLV 316_ MDPLQ 321_ TASVQ 326_ WFERT 331_ LDDSA 336_ NRRIC 341_ LAEAF 346_ LTADT 351_ ILNTL 356_ QNISE 361_ GLVVY 366_ PKVIE 371_ RRIRQ 376_ ELPFM 381_ ATENI 386_ IMAMV 391_ KAGGS 396_ RQDCH 401_ EKIRV 406_ LSQQA 411_ ASVVK 416_ QEGGD 421_ NDLIE 426_ RIQVD 431_ AYFSP 436_ IHSQL 441_ DHLLD 446_ PSSFT 451_ GRASQ 456_ QVQRF 461_ LEEEV 466_ YPLLK 471_ PYESV 476_MKVKA
1: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate