Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R)
1_MANSA 6_ SPEQN 11_ QNHCS 16_ AINNS 21_ IPLMQ 26_ GNLPT 31_ LTLSG 36_ KIRVT 41_ VTFFL 46_ FLLSA 51_ TFNAS 56_ FLLKL 61_ QKWTQ 66_ KKEKG 71_ KKLSR 76_ MKLLL 81_ KHLTL 86_ ANLLE 91_ TLIVM 96_ PLDGM 101_ WNITV 106_ QWYAG 111_ ELLCK 116_ VLSYL 121_ KLFSM 126_ YAPAF 131_ MMVVI 136_ SLDRS 141_ LAITR 146_ PLALK 151_ SNSKV 156_ GQSMV 161_ GLAWI 166_ LSSVF 171_ AGPQL 176_ YIFRM 181_ IHLAD 186_ SSGQT 191_ KVFSQ 196_ CVTHC 201_ SFSQW 206_ WHQAF 211_ YNFFT 216_ FSCLF 221_ IIPLF 226_ IMLIC 231_ NAKII 236_ FTLTR 241_ VLHQD 246_ PHELQ 251_ LNQSK 256_ NNIPR 261_ ARLKT 266_ LKMTV 271_ AFATS 276_ FTVCW 281_ TPYYV 286_ LGIWY 291_ WFDPE 296_ MLNRL 301_ SDPVN 306_ HFFFL 311_ FAFLN 316_ PCFDP 321_LIYGY
1: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling