Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
1_MDEEY 6_ DVIVL 11_ GTGLT 16_ ECILS 21_ GIMSV 26_ NGKKV 31_ LHMDR 36_ NPYYG 41_ GESSS 46_ ITPLE 51_ ELYKR 56_ FQLLE 61_ GPPES 66_ MGRGR 71_ DWNVD 76_ LIPKF 81_ LMANG 86_ QLVKM 91_ LLYTE 96_ VTRYL 101_ DFKVV 106_ EGSFV 111_ YKGGK 116_ IYKVP 121_ STETE 126_ ALASN 131_ LMGMF 136_ EKRRF 141_ RKFLV 146_ FVANF 151_ DENDP 156_ KTFEG 161_ VDPQT 166_ TSMRD 171_ VYRKF 176_ DLGQD 181_ VIDFT 186_ GHALA 191_ LYRTD 196_ DYLDQ 201_ PCLET 206_ VNRIK 211_ LYSES 216_ LARYG 221_ KSPYL 226_ YPLYG 231_ LGELP 236_ QGFAR 241_ LSAIY 246_ GGTYM 251_ LNKPV 256_ DDIIM 261_ ENGKV 266_ VGVKS 271_ EGEVA 276_ RCKQL 281_ ICDPS 286_ YIPDR 291_ VRKAG 296_ QVIRI 301_ ICILS 306_ HPIKN 311_ TNDAN 316_ SCQII 321_ IPQNQ 326_ VNRKS 331_ DIYVC 336_ MISYA 341_ HNVAA 346_ QGKYI 351_ AIAST 356_ TVETT 361_ DPEKE 366_ VEPAL 371_ ELLEP 376_ IDQKF 381_ VAISD 386_ LYEPI 391_ DDGCE 396_ SQVFC 401_ SCSYD 406_ ATTHF 411_ ETTCN 416_ DIKDI 421_ YKRMA 426_ GTAFD 431_ FENMK 436_ RKQND 441_VFGEA
1: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes