Mitogen-activated protein kinase 4 (MAP kinase 4) (MAPK 4) (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK)
1_MAEKG 6_ DCIAS 11_ VYGYD 16_ LGGRF 21_ VDFQP 26_ LGFGV 31_ NGLVL 36_ SAVDS 41_ RACRK 46_ VAVKK 51_ IALSD 56_ ARSMK 61_ HALRE 66_ IKIIR 71_ RLDHD 76_ NIVKV 81_ YEVLG 86_ PKGTD 91_ LQGEL 96_ FKFSV 101_ AYIVQ 106_ EYMET 111_ DLARL 116_ LEQGT 121_ LAEEH 126_ AKLFM 131_ YQLLR 136_ GLKYI 141_ HSANV 146_ LHRDL 151_ KPANI 156_ FISTE 161_ DLVLK 166_ IGDFG 171_ LARIV 176_ DQHYS 181_ HKGYL 186_ SEGLV 191_ TKWYR 196_ SPRLL 201_ LSPNN 206_ YTKAI 211_ DMWAA 216_ GCILA 221_ EMLTG 226_ RMLFA 231_ GAHEL 236_ EQMQL 241_ ILETI 246_ PVIRE 251_ EDKDE 256_ LLRVM 261_ PSFVS 266_ STWEV 271_ KRPLR 276_ KLLPE 281_ VNSEA 286_ IDFLE 291_ KILTF 296_ NPMDR 301_ LTAEM 306_ GLQHP 311_ YMSPY 316_ SCPED 321_ EPTSQ 326_ HPFRI 331_ EDEID 336_ DIVLM 341_ AANQS 346_ QLSNW 351_ DTCSS 356_ RYPVS 361_ LSSDL 366_ EWRPD 371_ RCQDA 376_ SEVQR 381_ DPRAG 386_ SAPLA 391_ EDVQV 396_ DPRKD 401_ SHSSS 406_ ERFLE 411_ QSHSS 416_ MERAF 421_ EADYG 426_ RSCDY 431_ KVGSP 436_ SYLDK 441_ LLWRD 446_ NKPHH 451_ YSEPK 456_ LILDL 461_ SHWKQ 466_ AAGAP 471_ PTATG 476_ LADTG 481_ AREDE 486_ PASLF 491_ LEIAQ 496_ WVKST 501_ QGGPE 506_ HASPP 511_ ADDPE 516_ RRLSA 521_ SPPGR 526_ PAPVD 531_ GGASP 536_ QFDLD 541_ VFISR 546_ ALKLC 551_ TKPED 556_ LPDNK 561_ LGDLN 566_ GACIP 571_ EHPGD 576_ LVQTE 581_AFSKE
1: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity)