Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2)
1_MASGN 6_ ARIGK 11_ PAPDF 16_ KATAV 21_ VDGAF 26_ KEVKL 31_ SDYKG 36_ KYVVL 41_ FFYPL 46_ DFTFV 51_ CPTEI 56_ IAFSN 61_ RAEDF 66_ RKLGC 71_ EVLGV 76_ SVDSQ 81_ FTHLA 86_ WINTP 91_ RKEGG 96_ LGPLN 101_ IPLLA 106_ DVTRR 111_ LSEDY 116_ GVLKT 121_ DEGIA 126_ YRGLF 131_ IIDGK 136_ GVLRQ 141_ ITVND 146_ LPVGR 151_ SVDEA 156_ LRLVQ 161_ AFQYT 166_ DEHGE 171_ VCPAG 176_ WKPGS 181_ DTIKP 186_ NVDDS 191_KEYFS
1: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)