Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R)
1_MDVVD 6_ SLLVN 11_ GSNIT 16_ PPCEL 21_ GLENE 26_ TLFCL 31_ DQPRP 36_ SKEWQ 41_ PAVQI 46_ LLYSL 51_ IFLLS 56_ VLGNT 61_ LVITV 66_ LIRNK 71_ RMRTV 76_ TNIFL 81_ LSLAV 86_ SDLML 91_ CLFCM 96_ PFNLI 101_ PNLLK 106_ DFIFG 111_ SAVCK 116_ TTTYF 121_ MGTSV 126_ SVSTF 131_ NLVAI 136_ SLERY 141_ GAICK 146_ PLQSR 151_ VWQTK 156_ SHALK 161_ VIAAT 166_ WCLSF 171_ TIMTP 176_ YPIYS 181_ NLVPF 186_ TKNNN 191_ QTANM 196_ CRFLL 201_ PNDVM 206_ QQSWH 211_ TFLLL 216_ ILFLI 221_ PGIVM 226_ MVAYG 231_ LISLE 236_ LYQGI 241_ KFEAS 246_ QKKSA 251_ KERKP 256_ STTSS 261_ GKYED 266_ SDGCY 271_ LQKTR 276_ PPRKL 281_ ELRQL 286_ STGSS 291_ SRANR 296_ IRSNS 301_ SAANL 306_ MAKKR 311_ VIRML 316_ IVIVV 321_ LFFLC 326_ WMPIF 331_ SANAW 336_ RAYDT 341_ ASAER 346_ RLSGT 351_ PISFI 356_ LLLSY 361_ TSSCV 366_ NPIIY 371_ CFMNK 376_ RFRLG 381_ FMATF 386_ PCCPN 391_ PGPPG 396_ ARGEV 401_ GEEEE 406_ GGTTG 411_ ASLSR 416_ FSYSH 421_MSASV
1: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system