CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70)
1_MPEEG 6_ SGCSV 11_ RRRPY 16_ GCVLR 21_ AALVP 26_ LVAGL 31_ VICLV 36_ VCIQR 41_ FAQAQ 46_ QQLPL 51_ ESLGW 56_ DVAEL 61_ QLNHT 66_ GPQQD 71_ PRLYW 76_ QGGPA 81_ LGRSF 86_ LHGPE 91_ LDKGQ 96_ LRIHR 101_ DGIYM 106_ VHIQV 111_ TLAIC 116_ SSTTA 121_ SRHHP 126_ TTLAV 131_ GICSP 136_ ASRSI 141_ SLLRL 146_ SFHQG 151_ CTIAS 156_ QRLTP 161_ LARGD 166_ TLCTN 171_ LTGTL 176_ LPSRN 181_ TDETF 186_FGVQW
1: Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells (PubMed:28011863, PubMed:28011864, PubMed:8387892). The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells (PubMed:28011863, PubMed:28011864)