ER lumen protein-retaining receptor 2 (ERD2-like protein 1) (ELP-1) (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2)
1_MNIFR 6_ LTGDL 11_ SHLAA 16_ IVILL 21_ LKIWK 26_ TRSCA 31_ GISGK 36_ SQLLF 41_ ALVFT 46_ TRYLD 51_ LFTSF 56_ ISLYN 61_ TSMKV 66_ IYLAC 71_ SYATV 76_ YLIYL 81_ KFKAT 86_ YDGNH 91_ DTFRV 96_ EFLVV 101_ PVGGL 106_ SFLVN 111_ HDFSP 116_ LEILW 121_ TFSIY 126_ LESVA 131_ ILPQL 136_ FMISK 141_ TGEAE 146_ TITTH 151_ YLFFL 156_ GLYRA 161_ LYLVN 166_ WIWRF 171_ YFEGF 176_ FDLIA 181_ VVAGV 186_ VQTIL 191_ YCDFF 196_ YLYIT 201_ KVLKG 206_KKLSL
1: Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi (PubMed:1325562, PubMed:18086916, PubMed:33053334). Binding is pH dependent, and is optimal at pH 5-5.4 (By similarity)