5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)
1_MMDVN 6_ SSGRP 11_ DLYGH 16_ LRSFL 21_ LPEVG 26_ RGLPD 31_ LSPDG 36_ GADPV 41_ AGSWA 46_ PHLLS 51_ EVTAS 56_ PAPTW 61_ DAPPD 66_ NASGC 71_ GEQIN 76_ YGRVE 81_ KVVIG 86_ SILTL 91_ ITLLT 96_ IAGNC 101_ LVVIS 106_ VCFVK 111_ KLRQP 116_ SNYLI 121_ VSLAL 126_ ADLSV 131_ AVAVM 136_ PFVSV 141_ TDLIG 146_ GKWIF 151_ GHFFC 156_ NVFIA 161_ MDVMC 166_ CTASI 171_ MTLCV 176_ ISIDR 181_ YLGIT 186_ RPLTY 191_ PVRQN 196_ GKCMA 201_ KMILS 206_ VWLLS 211_ ASITL 216_ PPLFG 221_ WAQNV 226_ NDDKV 231_ CLISQ 236_ DFGYT 241_ IYSTA 246_ VAFYI 251_ PMSVM 256_ LFMYY 261_ QIYKA 266_ ARKSA 271_ AKHKF 276_ PGFPR 281_ VEPDS 286_ VIALN 291_ GIVKL 296_ QKEVE 301_ ECANL 306_ SRLLK 311_ HERKN 316_ ISIFK 321_ REQKA 326_ ATTLG 331_ IIVGA 336_ FTVCW 341_ LPFFL 346_ LSTAR 351_ PFICG 356_ TSCSC 361_ IPLWV 366_ ERTFL 371_ WLGYA 376_ NSLIN 381_ PFIYA 386_ FFNRD 391_ LRTTY 396_ RSLLQ 401_ CQYRN 406_ INRKL 411_ SAAGM 416_ HEALK 421_ LAERP 426_ ERPEF 431_ VLRAC 436_ TRRVL 441_ LRPEK 446_ RPPVS 451_ VWVLQ 456_ SPDHH 461_ NWLAD 466_ KMLTT 471_VEKKV
1: G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35714614, PubMed:8226867). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors (PubMed:35714614, PubMed:8226867). HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity (PubMed:35714614)