Serpin B6 (Cytoplasmic antiproteinase) (CAP) (Peptidase inhibitor 6) (PI-6) (Placental thrombin inhibitor)
1_MDVLA 6_ EANGT 11_ FALNL 16_ LKTLG 21_ KDNSK 26_ NVFFS 31_ PMSMS 36_ CALAM 41_ VYMGA 46_ KGNTA 51_ AQMAQ 56_ ILSFN 61_ KSGGG 66_ GDIHQ 71_ GFQSL 76_ LTEVN 81_ KTGTQ 86_ YLLRM 91_ ANRLF 96_ GEKSC 101_ DFLSS 106_ FRDSC 111_ QKFYQ 116_ AEMEE 121_ LDFIS 126_ AVEKS 131_ RKHIN 136_ TWVAE 141_ KTEGK 146_ IAELL 151_ SPGSV 156_ DPLTR 161_ LVLVN 166_ AVYFR 171_ GNWDE 176_ QFDKE 181_ NTEER 186_ LFKVS 191_ KNEEK 196_ PVQMM 201_ FKQST 206_ FKKTY 211_ IGEIF 216_ TQILV 221_ LPYVG 226_ KELNM 231_ IIMLP 236_ DETTD 241_ LRTVE 246_ KELTY 251_ EKFVE 256_ WTRLD 261_ MMDEE 266_ EVEVS 271_ LPRFK 276_ LEESY 281_ DMESV 286_ LRNLG 291_ MTDAF 296_ ELGKA 301_ DFSGM 306_ SQTDL 311_ SLSKV 316_ VHKSF 321_ VEVNE 326_ EGTEA 331_ AAATA 336_ AIMMM 341_ RCARF 346_ VPRFC 351_ ADHPF 356_ LFFIQ 361_ HSKTN 366_ GILFC 371_GRFSS
1: May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss