Recoverin (Cancer-associated retinopathy protein) (Protein CAR)
1_MGNSK 6_ SGALS 11_ KEILE 16_ ELQLN 21_ TKFSE 26_ EELCS 31_ WYQSF 36_ LKDCP 41_ TGRIT 46_ QQQFQ 51_ SIYAK 56_ FFPDT 61_ DPKAY 66_ AQHVF 71_ RSFDS 76_ NLDGT 81_ LDFKE 86_ YVIAL 91_ HMTTA 96_ GKTNQ 101_ KLEWA 106_ FSLYD 111_ VDGNG 116_ TISKN 121_ EVLEI 126_ VMAIF 131_ KMITP 136_ EDVKL 141_ LPDDE 146_ NTPEK 151_ RAEKI 156_ WKYFG 161_ KNDDD 166_ KLTEK 171_ EFIEG 176_ TLANK 181_ EILRL 186_ IQFEP 191_QKVKE
1: Acts as a calcium sensor and regulates phototransduction of cone and rod photoreceptor cells (By similarity). Modulates light sensitivity of cone photoreceptor in dark and dim conditions (By similarity). In response to high Ca(2+) levels induced by low light levels, prolongs RHO/rhodopsin activation in rod photoreceptor cells by binding to and inhibiting GRK1-mediated phosphorylation of RHO/rhodopsin (By similarity). Plays a role in scotopic vision/enhances vision in dim light by enhancing signal transfer between rod photoreceptors and rod bipolar cells (By similarity). Improves rod photoreceptor sensitivity in dim light and mediates response of rod photoreceptors to facilitate detection of change and motion in bright light (By similarity)