Gene name: SFTPD

Uniprot entry:

P35247

Protein names:

Pulmonary surfactant-associated protein D (PSP-D) (SP-D) (Collectin-7) (Lung surfactant protein D)

Protein sequence:

1_MLLFL 6_ LSALV 11_ LLTQP 16_ LGYLE 21_ AEMKT 26_ YSHRT 31_ MPSAC 36_ TLVMC 41_ SSVES 46_ GLPGR 51_ DGRDG 56_ REGPR 61_ GEKGD 66_ PGLPG 71_ AAGQA 76_ GMPGQ 81_ AGPVG 86_ PKGDN 91_ GSVGE 96_ PGPKG 101_ DTGPS 106_ GPPGP 111_ PGVPG 116_ PAGRE 121_ GPLGK 126_ QGNIG 131_ PQGKP 136_ GPKGE 141_ AGPKG 146_ EVGAP 151_ GMQGS 156_ AGARG 161_ LAGPK 166_ GERGV 171_ PGERG 176_ VPGNT 181_ GAAGS 186_ AGAMG 191_ PQGSP 196_ GARGP 201_ PGLKG 206_ DKGIP 211_ GDKGA 216_ KGESG 221_ LPDVA 226_ SLRQQ 231_ VEALQ 236_ GQVQH 241_ LQAAF 246_ SQYKK 251_ VELFP 256_ NGQSV 261_ GEKIF 266_ KTAGF 271_ VKPFT 276_ EAQLL 281_ CTQAG 286_ GQLAS 291_ PRSAA 296_ ENAAL 301_ QQLVV 306_ AKNEA 311_ AFLSM 316_ TDSKT 321_ EGKFT 326_ YPTGE 331_ SLVYS 336_ NWAPG 341_ EPNDD 346_ GGSED 351_ CVEIF 356_ TNGKW 361_ NDRAC 366_GEKRL

Protein annotations

Protein functions:

1: Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties