Histamine H1 receptor (H1R) (HH1R)
1_MSLPN 6_ SSCLL 11_ EDKMC 16_ EGNKT 21_ TMASP 26_ QLMPL 31_ VVVLS 36_ TICLV 41_ TVGLN 46_ LLVLY 51_ AVRSE 56_ RKLHT 61_ VGNLY 66_ IVSLS 71_ VADLI 76_ VGAVV 81_ MPMNI 86_ LYLLM 91_ SKWSL 96_ GRPLC 101_ LFWLS 106_ MDYVA 111_ STASI 116_ FSVFI 121_ LCIDR 126_ YRSVQ 131_ QPLRY 136_ LKYRT 141_ KTRAS 146_ ATILG 151_ AWFLS 156_ FLWVI 161_ PILGW 166_ NHFMQ 171_ QTSVR 176_ REDKC 181_ ETDFY 186_ DVTWF 191_ KVMTA 196_ IINFY 201_ LPTLL 206_ MLWFY 211_ AKIYK 216_ AVRQH 221_ CQHRE 226_ LINRS 231_ LPSFS 236_ EIKLR 241_ PENPK 246_ GDAKK 251_ PGKES 256_ PWEVL 261_ KRKPK 266_ DAGGG 271_ SVLKS 276_ PSQTP 281_ KEMKS 286_ PVVFS 291_ QEDDR 296_ EVDKL 301_ YCFPL 306_ DIVHM 311_ QAAAE 316_ GSSRD 321_ YVAVN 326_ RSHGQ 331_ LKTDE 336_ QGLNT 341_ HGASE 346_ ISEDQ 351_ MLGDS 356_ QSFSR 361_ TDSDT 366_ TTETA 371_ PGKGK 376_ LRSGS 381_ NTGLD 386_ YIKFT 391_ WKRLR 396_ SHSRQ 401_ YVSGL 406_ HMNRE 411_ RKAAK 416_ QLGFI 421_ MAAFI 426_ LCWIP 431_ YFIFF 436_ MVIAF 441_ CKNCC 446_ NEHLH 451_ MFTIW 456_ LGYIN 461_ STLNP 466_ LIYPL 471_ CNENF 476_ KKTFK 481_RILHI
1: G-protein-coupled receptor for histamine, a biogenic amine that functions as an immune modulator and a neurotransmitter (PubMed:33828102, PubMed:8280179). Through the H1 receptor, histamine mediates the contraction of smooth muscles and increases capillary permeability due to contraction of terminal venules. Also mediates neurotransmission in the central nervous system and thereby regulates circadian rhythms, emotional and locomotor activities as well as cognitive functions (By similarity)