Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor)
1_MSTPG 6_ VNSSA 11_ SLSPD 16_ RLNSP 21_ VTIPA 26_ VMFIF 31_ GVVGN 36_ LVAIV 41_ VLCKS 46_ RKEQK 51_ ETTFY 56_ TLVCG 61_ LAVTD 66_ LLGTL 71_ LVSPV 76_ TIATY 81_ MKGQW 86_ PGGQP 91_ LCEYS 96_ TFILL 101_ FFSLS 106_ GLSII 111_ CAMSV 116_ ERYLA 121_ INHAY 126_ FYSHY 131_ VDKRL 136_ AGLTL 141_ FAVYA 146_ SNVLF 151_ CALPN 156_ MGLGS 161_ SRLQY 166_ PDTWC 171_ FIDWT 176_ TNVTA 181_ HAAYS 186_ YMYAG 191_ FSSFL 196_ ILATV 201_ LCNVL 206_ VCGAL 211_ LRMHR 216_ QFMRR 221_ TSLGT 226_ EQHHA 231_ AAAAS 236_ VASRG 241_ HPAAS 246_ PALPR 251_ LSDFR 256_ RRRSF 261_ RRIAG 266_ AEIQM 271_ VILLI 276_ ATSLV 281_ VLICS 286_ IPLVV 291_ RVFVN 296_ QLYQP 301_ SLERE 306_ VSKNP 311_ DLQAI 316_ RIASV 321_ NPILD 326_ PWIYI 331_ LLRKT 336_ VLSKA 341_ IEKIK 346_ CLFCR 351_ IGGSR 356_ RERSG 361_ QHCSD 366_ SQRTS 371_ SAMSG 376_ HSRSF 381_ ISREL 386_ KEISS 391_ TSQTL 396_ LPDLS 401_ LPDLS 406_ ENGLG 411_ GRNLL 416_ PGVPG 421_ MGLAQ 426_ EDTTS 431_ LRTLR 436_ ISETS 441_ DSSQG 446_ QDSES 451_ VLLVD 456_ EAGGS 461_ GRAGP 466_ APKGS 471_ SLQVT 476_ FPSET 481_LNLSE
1: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function