Thrombospondin-4
1_MLAPR 6_ GAAVL 11_ LLHLV 16_ LQRWL 21_ AAGAQ 26_ ATPQV 31_ FDLLP 36_ SSSQR 41_ LNPGA 46_ LLPVL 51_ TDPAL 56_ NDLYV 61_ ISTFK 66_ LQTKS 71_ SATIF 76_ GLYSS 81_ TDNSK 86_ YFEFT 91_ VMGRL 96_ NKAIL 101_ RYLKN 106_ DGKVH 111_ LVVFN 116_ NLQLA 121_ DGRRH 126_ RILLR 131_ LSNLQ 136_ RGAGS 141_ LELYL 146_ DCIQV 151_ DSVHN 156_ LPRAF 161_ AGPSQ 166_ KPETI 171_ ELRTF 176_ QRKPQ 181_ DFLEE 186_ LKLVV 191_ RGSLF 196_ QVASL 201_ QDCFL 206_ QQSEP 211_ LAATG 216_ TGDFN 221_ RQFLG 226_ QMTQL 231_ NQLLG 236_ EVKDL 241_ LRQQV 246_ KETSF 251_ LRNTI 256_ AECQA 261_ CGPLK 266_ FQSPT 271_ PSTVV 276_ PPAPP 281_ APPTR 286_ PPRRC 291_ DSNPC 296_ FRGVQ 301_ CTDSR 306_ DGFQC 311_ GPCPE 316_ GYTGN 321_ GITCI 326_ DVDEC 331_ KYHPC 336_ YPGVH 341_ CINLS 346_ PGFRC 351_ DACPV 356_ GFTGP 361_ MVQGV 366_ GISFA 371_ KSNKQ 376_ VCTDI 381_ DECRN 386_ GACVP 391_ NSICV 396_ NTLGS 401_ YRCGP 406_ CKPGY 411_ TGDQI 416_ RGCKA 421_ ERNCR 426_ NPELN 431_ PCSVN 436_ AQCIE 441_ ERQGD 446_ VTCVC 451_ GVGWA 456_ GDGYI 461_ CGKDV 466_ DIDSY 471_ PDEEL 476_ PCSAR 481_ NCKKD 486_ NCKYV 491_ PNSGQ 496_ EDADR 501_ DGIGD 506_ ACDED 511_ ADGDG 516_ ILNEQ 521_ DNCVL 526_ IHNVD 531_ QRNSD 536_ KDIFG 541_ DACDN 546_ CLSVL 551_ NNDQK 556_ DTDGD 561_ GRGDA 566_ CDDDM 571_ DGDGI 576_ KNILD 581_ NCPKF 586_ PNRDQ 591_ RDKDG 596_ DGVGD 601_ ACDSC 606_ PDVSN 611_ PNQSD 616_ VDNDL 621_ VGDSC 626_ DTNQD 631_ SDGDG 636_ HQDST 641_ DNCPT 646_ VINSA 651_ QLDTD 656_ KDGIG 661_ DECDD 666_ DDDND 671_ GIPDL 676_ VPPGP 681_ DNCRL 686_ VPNPA 691_ QEDSN 696_ SDGVG 701_ DICES 706_ DFDQD 711_ QVIDR 716_ IDVCP 721_ ENAEV 726_ TLTDF 731_ RAYQT 736_ VVLDP 741_ EGDAQ 746_ IDPNW 751_ VVLNQ 756_ GMEIV 761_ QTMNS 766_ DPGLA 771_ VGYTA 776_ FNGVD 781_ FEGTF 786_ HVNTQ 791_ TDDDY 796_ AGFIF 801_ GYQDS 806_ SSFYV 811_ VMWKQ 816_ TEQTY 821_ WQATP 826_ FRAVA 831_ EPGIQ 836_ LKAVK 841_ SKTGP 846_ GEHLR 851_ NSLWH 856_ TGDTS 861_ DQVRL 866_ LWKDS 871_ RNVGW 876_ KDKVS 881_ YRWFL 886_ QHRPQ 891_ VGYIR 896_ VRFYE 901_ GSELV 906_ ADSGV 911_ TIDTT 916_ MRGGR 921_ LGVFC 926_ FSQEN 931_ IIWSN 936_ LKYRC 941_ NDTIP 946_ EDFQE 951_ FQTQN 956_FDRFD
1: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner (By similarity)