Transcription factor SOX-11
1_MVQQA 6_ ESLEA 11_ ESNLP 16_ REALD 21_ TEEGE 26_ FMACS 31_ PVALD 36_ ESDPD 41_ WCKTA 46_ SGHIK 51_ RPMNA 56_ FMVWS 61_ KIERR 66_ KIMEQ 71_ SPDMH 76_ NAEIS 81_ KRLGK 86_ RWKML 91_ KDSEK 96_ IPFIR 101_ EAERL 106_ RLKHM 111_ ADYPD 116_ YKYRP 121_ RKKPK 126_ MDPSA 131_ KPSAS 136_ QSPEK 141_ SAAGG 146_ GGGSA 151_ GGGAG 156_ GAKTS 161_ KGSSK 166_ KCGKL 171_ KAPAA 176_ AGAKA 181_ GAGKA 186_ AQSGD 191_ YGGAG 196_ DDYVL 201_ GSLRV 206_ SGSGG 211_ GGAGK 216_ TVKCV 221_ FLDED 226_ DDDDD 231_ DDDEL 236_ QLQIK 241_ QEPDE 246_ EDEEP 251_ PHQQL 256_ LQPPG 261_ QQPSQ 266_ LLRRY 271_ NVAKV 276_ PASPT 281_ LSSSA 286_ ESPEG 291_ ASLYD 296_ EVRAG 301_ ATSGA 306_ GGGSR 311_ LYYSF 316_ KNITK 321_ QHPPP 326_ LAQPA 331_ LSPAS 336_ SRSVS 341_ TSSSS 346_ SSGSS 351_ SGSSG 356_ EDADD 361_ LMFDL 366_ SLNFS 371_ QSAHS 376_ ASEQQ 381_ LGGGA 386_ AAGNL 391_ SLSLV 396_ DKDLD 401_ SFSEG 406_ SLGSH 411_ FEFPD 416_ YCTPE 421_ LSEMI 426_ AGDWL 431_ EANFS 436_DLVFT
1: Transcription factor that acts as a transcriptional activator (PubMed:24886874, PubMed:26543203). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity)