Gene name: ATP6V1E1

Uniprot entry:

P36543

Protein names:

V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)

Protein sequence:

1_MALSD 6_ ADVQK 11_ QIKHM 16_ MAFIE 21_ QEANE 26_ KAEEI 31_ DAKAE 36_ EEFNI 41_ EKGRL 46_ VQTQR 51_ LKIME 56_ YYEKK 61_ EKQIE 66_ QQKKI 71_ QMSNL 76_ MNQAR 81_ LKVLR 86_ ARDDL 91_ ITDLL 96_ NEAKQ 101_ RLSKV 106_ VKDTT 111_ RYQVL 116_ LDGLV 121_ LQGLY 126_ QLLEP 131_ RMIVR 136_ CRKQD 141_ FPLVK 146_ AAVQK 151_ AIPMY 156_ KIATK 161_ NDVDV 166_ QIDQE 171_ SYLPE 176_ DIAGG 181_ VEIYN 186_ GDRKI 191_ KVSNT 196_ LESRL 201_ DLIAQ 206_ QMMPE 211_ VRGAL 216_ FGANA 221_NRKFL

Protein annotations

Protein functions:

1: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32001091, PubMed:33065002). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32001091)